Parrot bornavirus infection: correlation with neurological signs and feather picking?
Parrot bornavirus infection: correlation with neurological signs and feather picking?
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鹦鹉博纳病毒感染：与神经系统症状和羽毛采摘的相关性？
DOI：
10.1136/vr.l1089
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发表时间：
2019
影响因子：
2.2
通讯作者：
Horie Masayuki
中科院分区：
文献类型：
--
作者：
Junji Miyabe;Ryuichi Ohgaki;Keijiro Saito;Ling Wei;Suguru Okuda;Shushi Nagamori;Hiroshi Ohki;Kazuo Yoshino;Hidenori Inohara;Yoshikatsu Kanai;Okamura Y;Horie Masayuki
博尔纳病病毒是博尔纳病的病原体，其特征是由针对病毒抗原的细胞免疫应答引起的非化脓性脑膜脑脊髓炎。1该病毒因其与人类和动物健康的相关性而得到广泛研究。2-4直到2008年，在患有腺室扩张病（PDD）的鹦鹉中检测到遗传多样性的禽博尔纳病毒（ABV），它才成为博尔纳病毒科中唯一已知的病毒。PDD是一种在鹦鹉中观察到的致命疾病，在20世纪70年代首次被描述为金刚鹦鹉消耗病。从那时起，PDD和PDD样疾病已在80多种鸟类中报告，包括非鹦鹉鸟类，如巨嘴鸟，水禽和金丝雀。5，6 PDD感染的禽类表现出胃肠道症状，如粪便中未消化的食物、呕吐和体重减轻，和/或神经系统症状，如抑郁、共济失调和失明。组织学上，PDD的特征是外周和/或中枢神经系统中的淋巴浆细胞浸润。7这种炎症和由此导致的肌间神经的破坏被认为是胃肠功能障碍的原因。尽管PDD多年来一直被认为是一种传染病，但直到ABV被发现，其病因仍不清楚。几乎同时发表的两份报告详细描述了在受PDD影响的鸟类中发现ABV的情况，8，9其中一份报告显示ABV感染与PDD之间存在统计学关联。9在这些报道之后，在细胞培养物中分离ABV并用作实验感染的接种物以确定ABV是否确实是PDD的病原体。其中一些研究表明，鹦鹉博纳病毒2和4（PaBV-2和4）是PDD的病原体。10-13
BORNA disease virus is the causative agent of Borna disease, which is characterised by nonsuppurative meningoencephalomyelitis caused by cellular immune responses against the viral antigens. 1 This virus has been extensively studied because of its relevance to both human and animal health. 2-4 It was the only virus known in the family Bornaviridae until 2008, when genetically diverse avian bornaviruses (ABVs) were detected in psittacine birds with proventricular dilatation disease (PDD). PDD is a fatal disease observed in psittacine birds and was first described as macaw wasting disease in the 1970s. Since then, PDD and PDD-like diseases have been reported in more than 80 species of birds, including non-psittacine birds such as toucans, waterfowl and canaries. 5, 6 PDD-affected birds show gastrointestinal signs such as undigested food in the faeces, vomiting, and weight loss and/or neurological signs such as depression, ataxia and blindness. 7 Histopathologically, PDD is characterised by lymphoplasmacytic infiltration in the peripheral and/or central nervous system. 7 Such inflammation and the resultant destruction of myenteric nerves are considered to be the cause of gastrointestinal dysfunction. 6 Although PDD had been considered an infectious disease for many years, the aetiological agent remained unknown until ABVs were discovered. Two reports published at almost the same time detailed the discoveries of ABVs in PDD-affected birds, 8, 9 with one of these demonstrating a statistical association between ABV infection and PDD. 9 Following these reports, ABVs were isolated in cell culture and used as the inoculum for experimental infections to determine whether ABVs were indeed the aetiological agent of PDD. Several of these studies revealed that parrot bornavirus 2 and 4 (PaBV-2 and 4) are causative agents of PDD. 10-13
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影响因子：
5.4
作者：
Rinder, Monika;Ackermann, Andreas;Staeheli, Peter
通讯作者：
Staeheli, Peter
影响因子：
1.3
作者：
Murray, Maureen;Guo, Jianhua;O'Brien, Kathleen M.
通讯作者：
O'Brien, Kathleen M.
禽博纳病毒特异性抗体和病毒核糖核酸脱落与鹦鹉鸟类神经系统症状和羽毛损伤行为的相关性
DOI：
10.1136/vr.104860
发表时间：
2019
期刊：
The Veterinary Record
影响因子：
--
作者：
A. Fluck;D. Enderlein;A. Piepenbring;U. Heffels;S. Herzog;Kay Pieper;C. Herden;M. Lierz
通讯作者：
M. Lierz
影响因子：
0.9
作者：
Christopher R;K. Latimer;F. Niagro;B. Ritchie;Raymond P. Campagnoil;T. Norton;R. McManamon;C. Greenacre
通讯作者：
C. Greenacre
DOI：
10.1016/j.cvex.2013.10.002
发表时间：
2014-01-01
期刊：
Veterinary Clinics of North America Exotic Animal Practice
影响因子：
--
作者：
Rubinstein, Jonathan;Lightfoot, Teresa
通讯作者：
Lightfoot, Teresa