Social impairment in relation to clinical symptoms in youth at high risk for bipolar disorder.
Social impairment in relation to clinical symptoms in youth at high risk for bipolar disorder.
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DOI：
10.1111/eip.13124
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发表时间：
2022-01
影响因子：
2
通讯作者：
Miklowitz DJ
中科院分区：
文献类型：
--
作者：
Weintraub MJ;Keenan-Miller D;Schneck CD;Forgey Borlik M;Suddath RL;Marvin SE;Singh MK;Chang KD;Miklowitz DJ
社交障碍在双相情感障碍（BD）患者中很常见，尽管它在BD高危青年中的作用（即，在BD家族史的背景下的情绪症状）还没有得到很好的理解。社交障碍有多种形式，包括社交退缩，关系攻击，身体攻击和受害。本研究的目的是探讨BD高危青年的社会功能障碍和临床症状之间的联系。样本包括127名情绪症状（抑郁或轻躁狂）升高的年轻人，以及至少一名BD的一级和/或二级亲属。青少年目前的精神病理学指标（即，抑郁和躁狂的严重程度、自杀倾向、焦虑和注意力缺陷/多动障碍[ADHD]）回归到青少年对社会损害的自我报告（即，社会退缩、关系攻击、身体攻击和受害）。抑郁症状、自杀意念和焦虑症状与社交退缩有关。自杀意念也与反应性攻击有关。ADHD症状与反应性和主动性攻击以及关系受害有关。躁狂症状与该样本中的社交障碍无关。虽然是横断面的，但研究结果指出了与社会功能相关的潜在治疗目标。具体来说，社交退缩应该是治疗儿童抑郁和焦虑症状的目标。关注与BD相关的社交技能和认知功能缺陷的治疗也可能具有临床实用性。
Social impairment is common in individuals with bipolar disorder (BD), although its role in youths at high-risk for BD (i.e., mood symptoms in the context of a family history of BD) is not well understood. Social impairment takes many forms including social withdrawal, relational aggression, physical aggression, and victimization. The aim of this study was to explore the links between social impairment and clinical symptoms in youth at high-risk for BD. The sample included 127 youths with elevations in mood symptoms (depression or hypomania) and at least one first and/or second degree relative with BD. Measures of youths’ current psychopathology (i.e., depressive and manic severity, suicidality, anxiety, and attention-deficit/hyperactivity disorder [ADHD]) were regressed onto youths’ self-reports of social impairment (i.e., social withdrawal, relational aggression, physical aggression, and victimization). Depressive symptoms, suicidal ideation, and anxiety symptoms were related to social withdrawal. Suicidal ideation was also related to reactive aggression. ADHD symptoms related to reactive and proactive aggression as well as relational victimization. Manic symptoms were not associated with social impairment in this sample. Although cross-sectional, study findings point to potential treatment targets related to social functioning. Specifically, social withdrawal should be a target for treatment of childhood depressive and anxiety symptoms. Treatments that focus on social skills and cognitive functioning deficits associated with BD may also have clinical utility.
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