Determination of oxytetracycline residues in cattle meat marketed in the Kilosa district, Tanzania.
Determination of oxytetracycline residues in cattle meat marketed in the Kilosa district, Tanzania.
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DOI：
10.4102/ojvr.v82i1.911
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发表时间：
2015-11-27
期刊：
影响因子：
--
通讯作者：
Mwesongo J
中科院分区：
文献类型：
--
作者：
Kimera ZI;Mdegela RH;Mhaiki CJ;Karimuribo ED;Mabiki F;Nonga HE;Mwesongo J
土霉素用于治疗牛的各种疾病。然而，它的使用可能与食物中不可接受的残留水平有关。2012年11月至2013年4月期间，在坦桑尼亚基洛萨地区进行了一项横断面研究，确定了土着牛组织中的土霉素残留。从屠宰场和屠夫共收集了60份组织样本，包括肌肉、肝脏和肾脏，并使用高效液相色谱法分析了土环素。71.1%的样品中检出土霉素残留，其中68.3%的样品高于可接受的监管水平。土霉素跨组织平均浓度为3401.1µg/kg±879.3µg/kg；在肌肉、肝脏和肾脏中的浓度分别为2604.1µg/kg±703.7µg/kg、3434.4µg/kg±606.4µg/kg和3533.1µg/kg±803.6µg/kg。本地牛肉中土霉素残留量高可能对基洛萨消费者的健康构成威胁。调查结果可能反映了普遍缺乏对建议的停药期的执行，对药物使用的无知和缺乏推广服务。需要对畜牧业中抗菌药物的使用进行严格监管，并在销售前对动物源性食品源进行相关检测。
Oxytetracycline is used to treat various diseases in cattle. However, its use may be associated with unacceptable residue levels in food. Oxytetracycline residues in tissues from indigenous cattle were determined in a cross-sectional study conducted in the Kilosa district, Tanzania, between November 2012 and April 2013. A total of 60 tissue samples, including muscle, liver and kidney, were collected from slaughterhouses and butchers and analysed for oxytetracycline using high-performance liquid chromatography. Oxytetracycline residues were found in 71.1% of the samples, of which 68.3% were above acceptable regulatory levels. The mean concentration of oxytetracycline across tissues was 3401.1 µg/kg ± 879.3 µg/kg; concentrations in muscle, liver and kidney were 2604.1 µg/kg ± 703.7 µg/kg, 3434.4 µg/kg ± 606.4 µg/kg and 3533.1 µg/kg ± 803.6 µg/kg, respectively. High levels of oxytetracycline residue in meat from indigenous cattle may pose a health threat to consumers in Kilosa. The findings possibly reflect a general lack of implementation of recommended withdrawal periods, ignorance about drug use and lack of extension services. Strict regulation of the use of antimicrobial drugs in the livestock industry and associated testing of animal-derived food sources prior to marketing are required.
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影响因子：
3.6
作者：
Abbasi, Mehran Mesgari;Babaei, Hossein;Nemati, Mahboob
通讯作者：
Nemati, Mahboob
DOI：
10.1590/s0100-40422011000100009
发表时间：
2011-01-01
期刊：
Química Nova
影响因子：
--
作者：
Uekane, Thais Matsue;Aquino Neto, Francisco Radler;Gomes, Luiz Nelson F
通讯作者：
Gomes, Luiz Nelson F
DOI：
10.3923/pjn.2009.203.207
发表时间：
2009-01-01
期刊：
Pakistan Journal of Nutrition
影响因子：
--
作者：
Nonga, H. E.;Mariki, M.;Mdegela, R. H.
通讯作者：
Mdegela, R. H.
影响因子：
2.6
作者：
Mellau, L. S. B.;Nonga, H. E.;Karimuribo, E. D.
通讯作者：
Karimuribo, E. D.
影响因子：
2.4
作者：
Nonga, H. E.;Simon, C.;Mdegela, R. H.
通讯作者：
Mdegela, R. H.