Recent Progress of Magnetically Actuated DNA Micro/Nanorobots.
Recent Progress of Magnetically Actuated DNA Micro/Nanorobots.
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磁驱动DNA微纳米机器人的最新进展
DOI：
10.34133/2022/9758460
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
中科院分区：
文献类型：
--
作者：
在过去的几十年里，基于DNA折纸的微纳米技术以其高度的完整性、刚性的结构和优异的抗酶消化能力得到了迅速的发展，并日益受到人们的关注。许多二维和三维DNA纳米结构与光学，化学或磁性触发器协调已被设计和组装，广泛用作分子机器人，纳米传感器和细胞内药物递送的通用模板。磁场被广泛认为是微/纳米材料的理想驱动和操作系统，因为它不需要像光控那样的高强度激光，也不需要像化学活化那样改变化学成分。在此，我们回顾了最近的成就，在感应和驱动的DNA折纸为基础的纳米器件，响应磁场。这些基于磁致动的DNA纳米器件定期与磁珠或金纳米颗粒结合，并用于产生单链支架，组装各种DNA纳米结构，并纯化特定的DNA纳米结构。此外，它们还产生人工磁性或在外部磁场的驱动下有规律地运动，以解释更深层次的科学问题。
In the past few decades, the field of DNA origami-based micro/nanotechnology has developed dramatically and spawned attention increasingly, as its high integrality, rigid structure, and excellent resistance ability to enzyme digestion. Many two-dimensional and three-dimensional DNA nanostructures coordinated with optical, chemical, or magnetic triggers have been designed and assembled, extensively used as versatile templates for molecular robots, nanosensors, and intracellular drug delivery. The magnetic field has been widely regarded as an ideal driving and operating system for micro/nanomaterials, as it does not require high-intensity lasers like light control, nor does it need to change the chemical composition similar to chemical activation. Herein, we review the recent achievements in the induction and actuation of DNA origami-based nanodevices that respond to magnetic fields. These magnetic actuation-based DNA nanodevices were regularly combined with magnetic beads or gold nanoparticles and applied to generate single-stranded scaffolds, assemble various DNA nanostructures, and purify specific DNA nanostructures. Moreover, they also produced artificial magnetism or moved regularly driven by external magnetic fields to explain deeper scientific issues.
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DOI：
10.1126/science.1226734
发表时间：
2012-11-02
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Derr ND;Goodman BS;Jungmann R;Leschziner AE;Shih WM;Reck-Peterson SL
通讯作者：
Reck-Peterson SL
影响因子：
29.4
作者：
Donolato, Marco;Vavassori, Paolo;Bertacco, Riccardo
通讯作者：
Bertacco, Riccardo
影响因子：
14.9
作者：
Douglas SM;Marblestone AH;Teerapittayanon S;Vazquez A;Church GM;Shih WM
通讯作者：
Shih WM
影响因子：
56.9
作者：
Acuna, G. P.;Moeller, F. M.;Tinnefeld, P.
通讯作者：
Tinnefeld, P.
影响因子：
64.8
作者：
Douglas, Shawn M.;Dietz, Hendrik;Liedl, Tim;Hoegberg, Bjoern;Graf, Franziska;Shih, William M.
通讯作者：
Shih, William M.