Sequential Acquisition of Human Papillomavirus Infection at Genital and Anal Sites, Liuzhou, China.

Sequential Acquisition of Human Papillomavirus Infection at Genital and Anal Sites, Liuzhou, China.
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中国柳州生殖器和肛门部位人乳头瘤病毒感染的连续采集

DOI:
10.3201/eid2610.191646
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发表时间:
2020-10
影响因子:
11.8
通讯作者:
Xia N
Xia N
中科院分区:
医学2区
文献类型:
--
作者:
Wei F;Su Y;Cui X;Yu X;Li Y;Song Q;Yin K;Huang S;Li M;Zhang J;Wu T;Xia N

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对于肛门(或生殖器)HPV 感染后在生殖器(或肛门)部位感染人乳头瘤病毒(HPV)的风险知之甚少。我们每隔 6 个月从中国柳州的 2,309 名男性和 2,378 名女性采集 3 组肛门生殖器样本,并对这些样本进行 HPV 检测。既往生殖器 HPV 感染的参与者连续肛门 HPV 感染的风险高于未感染的参与者(女性风险比 [HR] 4.4,95% CI 3.4-5.8,男性 HR 2.6,95% CI 1.4-4.6)。对于连续性生殖器 HPV 感染,以前有肛门感染的女性风险较高(HR 1.9,95% CI 1.2-3.1),但男性没有发现重大差异(HR 0.7,95% CI 0.2-1.9)。我们的研究表明,除了直接性交外,自身接种可能在肛门生殖器 HPV 传播中发挥重要作用,特别是对于女性肛门感染。
Little is known about the risk for acquiring a concordant human papillomavirus (HPV) infection in a genital (or anal) site after an anal (or genital) HPV infection. We collected 3 sets of anogenital specimens at 6-month intervals from 2,309 men and 2,378 women in Liuzhou, China, and tested these specimens for HPV. The risk for sequential anal HPV infection in participants with a previous genital HPV infection was higher than for participants without an infection (hazard ratio [HR] 4.4, 95% CI 3.4–5.8 for women and HR 2.6, 95% CI 1.4–4.6 for men). For sequential genital HPV infection, women with a previous anal infection had a higher risk (HR 1.9, 95% CI 1.2–3.1), but no major difference was found for men (HR 0.7, 95% CI 0.2–1.9). Our study indicates that autoinoculation might play a major role in anogenital HPV transmission, in addition to direct sexual intercourse, especially for anal infection in women.
DOI: 10.1016/s1470-2045(14)70481-4
发表时间: 2015-05-01
期刊: LANCET ONCOLOGY
影响因子: 51.1
作者:
Herrero, Rolando;Gonzalez, Paula;Markowitz, Lauri E.
通讯作者: Markowitz, Lauri E.
DOI: 10.1086/651620
发表时间: 2010-05-01
期刊: The Journal of infectious diseases
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Goodman MT;Shvetsov YB;McDuffie K;Wilkens LR;Zhu X;Thompson PJ;Ning L;Killeen J;Kamemoto L;Hernandez BY
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中国柳州男性和女性不同肛门生殖部位人乳头瘤病毒感染的流行率和一致性:一项基于人群的研究
DOI: 10.1002/ijc.31128
发表时间: 2018-03-15
影响因子: 6.4
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发表时间: 2019-08-01
影响因子: 56.3
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通讯作者: Clifford, Gary M.
DOI: 10.1136/sti.75.5.317
发表时间: 1999-10-01
影响因子: 3.6
作者:
Sonnex, C;Strauss, S;Gray, JJ
通讯作者: Gray, JJ