Peripheral colour contrast thresholds in ocular hypertension and glaucoma.
Peripheral colour contrast thresholds in ocular hypertension and glaucoma.
复制标题
高眼压症和青光眼的周边颜色对比阈值。
DOI：
10.1111/j.1600-0420.1997.tb00393.x
复制
发表时间：
2009
期刊：
影响因子：
--
通讯作者：
B. Friström
中科院分区：
文献类型：
--
作者：
B. Friström
目的
目的：评价一种新的周边色对比敏感度检测方法作为青光眼早期诊断的方法。
患者和方法
用Arden等人开发的计算机和彩色监视器系统测量外周颜色对比敏感度。监视器显示视网膜上有一个25度的环。在测试过程中，在四个象限中的一个象限中移除45度的环状结构。患者被要求首先以高于阈值的水平识别这个象限，然后由于环和背景之间的颜色对比度不同，以便建立识别阈值。测试的颜色分别沿着Protan、Deutan和Tritan混色轴变化。对33例正常人、22例青光眼患者和69例高眼压患者进行了检查。将高眼压患者分为低危组、中危组和高危组。
结果
青光眼组和高危高眼压组的三个色轴的颜色对比阈值均显著高于正常组(p<；0.001)。青光眼组和高眼压低危组之间的所有眼轴也有显著差异(P<；0.05-0.001)。然而，所有组之间的颜色对比度阈值都有重叠。
结论
尽管正常人和青光眼患者的平均颜色对比度阈值有很大且有统计学意义的差异，但很难找到一个适当的分界点来区分两组。进一步的研究必须阐明常见疾病的早期阶段，如白内障、糖尿病和老年性黄斑病变对颜色对比敏感度的影响。
PURPOSE
To evaluate a new test for peripheral colour contrast sensitivity as a tool for early diagnosis of glaucoma.
PATIENTS AND METHODS
Peripheral colour contrast sensitivity was measured by a computer and colour monitor system developed by Arden and co-workers. The monitor displays an annulus subtending 25 degrees at the retina. During the test, 45 degrees of the annulus is removed in one of four quadrants. The patient is asked to identify this quadrant, first at suprathreshold levels and then as the colour contrast between the annulus and the background is varied in order to establish the threshold for identification. The tested colours were varied along the protan, deutan and tritan colour confusion axes, respectively. Thirty-three normal subjects, 22 glaucoma patients and 69 ocular hypertensive patients were examined. The ocular hypertensive patients were divided into a low risk group, a medium risk group and a high risk group.
RESULTS
The colour contrast thresholds for the glaucoma group and the high risk ocular hypertensive group were significantly (p < 0.001) higher for all three colour axes compared with the normal group. There were also significant (p < 0.05-0.001) differences for all axes between the glaucoma group on the one hand and the ocular hypertensive low risk group on the other hand. There were, however, overlaps in colour contrast thresholds between all groups.
CONCLUSION
Although there is a large and statistically significant difference in average colour contrast thresholds between normals and glaucoma patients, it was difficult to find an appropriate cut-off point to separate the two groups. Further studies must clarify the influence of early stages of common diseases such as cataract, diabetes and age-related maculopathy on colour contrast sensitivity.
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影响因子：
--
作者：
SOMMER, A;TIELSCH, JM;SINGH, K
通讯作者：
SINGH, K
影响因子：
4.4
作者：
Anthony J. Adams;Rosemary Rodic;R. Husted;Robert;Stamper
通讯作者：
Anthony J. Adams;Rosemary Rodic;R. Husted;Robert;Stamper
眼部疾病的新临床颜色阈值测试。
DOI：
10.1097/00006324-198701000-00005
发表时间：
1987
期刊：
American journal of optometry and physiological optics
影响因子：
--
作者：
Adams,AJ;Schefrin,B;Huie,K
通讯作者：
Huie,K
青光眼进行性彩色视野丧失。
影响因子：
4.4
作者：
Sample,PA;Weinreb,RN
通讯作者：
Weinreb,RN
青光眼自动阈上筛查：巴尔的摩眼科调查。
影响因子：
4.4
作者：
Katz,J;Tielsch,JM;Quigley,HA;Javitt,J;Witt,K;Sommer,A
通讯作者：
Sommer,A