Inequalities in the uptake of human papillomavirus vaccination: a systematic review and meta-analysis.
Inequalities in the uptake of human papillomavirus vaccination: a systematic review and meta-analysis.
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DOI：
10.1093/ije/dyt049
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发表时间：
2013-06
影响因子：
7.7
通讯作者：
Hickman M
中科院分区：
文献类型：
--
作者：
Fisher H;Trotter CL;Audrey S;MacDonald-Wallis K;Hickman M
人类乳头瘤病毒（HPV）疫苗提供了一个机会，以减少与宫颈癌相关的健康不平等，前提是疫苗在人口水平上公平地提供。方法我们回顾了从成立到2012年3月对数据库进行全面检索后，年轻女性HPV疫苗接种不平等的证据。纳入了通过至少一个种族或社会经济相关变量比较青春期年轻女性HPV疫苗接种开始和/或完成的研究。没有语言限制。由两名评审员提取数据，并使用随机效应模型进行荟萃分析;进行子分析和荟萃回归以调查异质性的来源。结果共纳入29篇文献，涉及27项研究。与白色年轻女性相比，黑人年轻女性启动HPV疫苗接种的可能性较小（合并OR：0.89，95% CI：0.82-0.97）。在美国，没有医疗保险的年轻女性不太可能开始（合并OR：0.56，95% CI：0.40-0.78）。没有强有力的证据表明较低的家庭收入（合并OR：1.16，95% CI：1.00-1.34）或较低的父母教育程度（合并OR：1.06，95% CI：0.92-1.22）影响HPV疫苗接种的开始。结论：我们发现了强有力的证据表明，不同种族和医疗覆盖率的HPV疫苗接种开始存在差异，但没有发现与父母教育或家庭收入变量的强相关性。大多数研究来自美国。需要进行基于人群的研究，报告HPV疫苗接种计划的启动和完成情况，以建立不同医疗保健背景下的接种模式。
Background The human papillomavirus (HPV) vaccine offers an opportunity to reduce health inequalities associated with cervical cancer provided the vaccine is delivered equitably at population level. Method We reviewed evidence of inequalities in HPV vaccine uptake in young women after undertaking a comprehensive search of databases from inception to March 2012. Studies that compared HPV vaccination initiation and/or completion by at least one ethnicity or socioeconomic-related variable in adolescent young women were included. There were no language restrictions. Data were extracted by two reviewers and pooled in a meta-analysis using a random-effects model; sub-analyses and meta-regression were undertaken to investigate sources of heterogeneity. Results In all, 29 publications related to 27 studies were included in the review. Black young women were less likely to initiate HPV vaccination compared with White young women (combined OR: 0.89, 95% CI: 0.82–0.97). In the USA, young women without healthcare insurance were less likely to initiate (combined OR: 0.56, 95% CI: 0.40–0.78). There was no strong evidence that lower family income (combined OR: 1.16, 95% CI: 1.00–1.34) or lower parental education (combined OR 1.06, 95% CI: 0.92–1.22) influenced HPV vaccination initiation. Conclusions We found strong evidence for differences in HPV vaccination initiation by ethnicity and healthcare coverage, but did not find a strong association with parental education or family income variables. The majority of studies originated from the USA. Population-based studies reporting both initiation and completion of the HPV vaccination programme are required to establish patterns of uptake in different healthcare contexts.
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了解少数民族女孩中次优的人乳头瘤病毒疫苗的摄取。
DOI：
10.1158/1055-9965.epi-11-0267
发表时间：
2011-07
期刊：
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
影响因子：
--
作者：
Bastani R;Glenn BA;Tsui J;Chang LC;Marchand EJ;Taylor VM;Singhal R
通讯作者：
Singhal R
影响因子：
8
作者：
Dorell, Christina G.;Yankey, David;Markowitz, Lauri E.
通讯作者：
Markowitz, Lauri E.
影响因子：
8.9
作者：
Chao, Chun;Velicer, Chrstine;Jacobsen, Steven J.
通讯作者：
Jacobsen, Steven J.
影响因子：
5.1
作者：
Gold, Rachel;Naleway, Allison L.;Kurilo, Mary Beth
通讯作者：
Kurilo, Mary Beth
影响因子：
2.8
作者：
Mathur, Maya B.;Mathur, Vandana S.;Reichling, David B.
通讯作者：
Reichling, David B.