The association between plant-based dietary patterns and risk of breast cancer: a case-control study.

The association between plant-based dietary patterns and risk of breast cancer: a case-control study.
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DOI:
10.1038/s41598-021-82659-6
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发表时间:
2021-02-09
期刊:
影响因子:
4.6
通讯作者:
Esmaillzadeh A
Esmaillzadeh A
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Rigi S;Mousavi SM;Benisi-Kohansal S;Azadbakht L;Esmaillzadeh A

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现有的数据有限,将植物性饮食与乳腺癌(BC)联系起来。我们研究了伊朗女性总体植物性饮食指数(PDI)、假设健康(hPDI)和不健康植物性饮食指数(uPDI)与BC的关系。这项以人群为基础的病例对照研究包括350例新诊断的BC病例和700例年龄匹配的表面健康对照。我们使用经过验证的willett格式半定量食物频率问卷收集饮食数据。利用这些数据,我们生成了将正分值赋给植物性食品、将反分值赋给动物性食品的PDI,将正分值赋给健康植物性食品、将反分值赋给不太健康的植物性食品和动物性食品的hPDI,以及将正分值赋给不健康植物性食品、将反分值赋给健康植物性食品和动物性食品的uPDI。在控制了潜在的混杂因素后,PDI最高四分位数的个体比最低四分位数的个体患BC的几率低67% (OR 0.33; 95% CI 0.22-0.50)。在完全调整的模型中,最坚持hPDI的个体比最低坚持的个体患BC的可能性低36% (OR 0.64; 95% CI 0.43-0.94)。就uPDI而言,前四分位数的女性患BC的几率是后四分位数的2.23倍(OR 2.23; 95% CI 1.48-3.36)。更坚持PDI和hPDI与BC风险呈负相关,而uPDI与风险增加相关。
Limited data are available, linking the plant-based diets to breast cancer (BC). We examined the association of overall plant-based diet index (PDI), hypothesized healthful (hPDI) and unhealthful versions of a plant-based diet index (uPDI) with BC in Iranian women. This population-based case–control study included 350 cases with newly diagnosed BC and 700 age-matched apparently healthy controls. We collected dietary data using a validated, Willett-format semi-quantitative food frequency questionnaire. Using these data, we generated a PDI by dedicating positive scores to plant foods, and reverse scores to animal foods, hPDI by assigning positive scores to healthy plant foods and reverse scores to less healthy plant foods and animal foods, and finally uPDI in which positive scores were assigned to less healthy plant foods and reverse scores to healthy plant foods and animal foods. After controlling for potential confounders, individuals in the highest quartile of PDI had 67% lower odds of BC than those in the lowest quartile (OR 0.33; 95% CI 0.22–0.50). Individuals with the greatest adherence to hPDI were 36% less likely to have BC than those with the lowest adherence, in the fully adjusted model (OR 0.64; 95% CI 0.43–0.94). In terms of uPDI, women in the top quartile had a 2.23 times greater chance of BC than those in the bottom quartile (OR 2.23; 95% CI 1.48–3.36). Greater adherence to PDI and hPDI was inversely associated with the risk of BC, whereas uPDI was associated with an increased risk.
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期刊: Asian Pacific journal of cancer prevention : APJCP
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