The Value of Optical Coherence Tomography Angiography (OCT-A) in Neurological Diseases.

The Value of Optical Coherence Tomography Angiography (OCT-A) in Neurological Diseases.
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DOI:
10.3390/diagnostics12020468
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发表时间:
2022-02-11
期刊:
Diagnostics (Basel, Switzerland)
影响因子:
--
通讯作者:
Atorf J
Atorf J
中科院分区:
其他
文献类型:
--
作者:
Augustin AJ;Atorf J

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光学相干断层扫描血管造影术(OCT-A)于2014年投入商业使用。OCT-A允许对从玻璃体视网膜界面到脉络膜毛细血管的视网膜血管系统进行快速、非侵入性的三维分析。结果可以在自动或自定义的视网膜层中单独评估。自推出以来,OCT-A也已用于神经系统疾病患者,以发现和表征视网膜生物标志物。许多神经系统疾病具有视网膜表现,通常在神经系统疾病的关键症状之前。从解剖学和发育学上讲,视网膜是大脑的一部分。与大脑相比,视网膜很容易获得成像方法;此外,视网膜成像比大脑成像更具成本效益。本文就OCT-A在神经系统疾病中的诊断价值进行了综述和讨论。
Optical coherence tomography angiography (OCT-A) was commercially introduced in 2014. OCT-A allows a fast, non-invasive, three-dimensional analysis of the retinal vasculature from the vitreoretinal interface to the choriocapillaris. The results can be evaluated separately in automated or custom-defined retinal layers. Since its introduction, OCT-A has also been used in patients with neurological diseases in order to find and characterize retinal biomarkers. Many neurological diseases have retinal manifestations, often preceding the key symptoms of the neurological disease. Anatomically and developmentally, the retina is a part of the brain. In contrast to the brain, the retina is easily accessible for imaging methods; moreover, retinal imaging is more cost-effective than brain imaging. In this review, the current knowledge about OCT-A findings and possible OCT-A biomarkers in neurological diseases is summarized and discussed regarding the value of OCT-A as a diagnostic tool in neurological diseases.
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