The effects of dietary protein and amino acids on skeletal metabolism.
The effects of dietary protein and amino acids on skeletal metabolism.
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DOI：
10.1016/j.mce.2015.03.024
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发表时间：
2015-07-15
影响因子：
4.1
通讯作者：
Insogna KL
中科院分区：
文献类型：
--
作者：
Bihuniak JD;Insogna KL
膳食蛋白质是最佳骨骼生长和成熟所必需的。虽然存在全球膳食蛋白质摄入量的推荐膳食允许量（RDA），但尚未确定在生命连续体中对骨骼健康最佳的膳食蛋白质水平和来源。这部分是由于难以量化一生中不同营养素摄入水平的影响，以及膳食蛋白质和钙经济之间关系的复杂性。目前不确定的领域包括最佳骨骼增长和维持骨骼质量所需的膳食蛋白质的确切来源和数量，以及膳食蛋白质的特定部位效应。膳食蛋白质对矿物质代谢和骨骼稳态作用的细胞和分子机制仍不清楚。本文试图总结与这些问题有关的最新数据。
Dietary protein is required for optimal skeletal growth and maturation. Although Recommended Dietary Allowances (RDAs) exist for global dietary protein intake, the level and sources of dietary protein that are optimal for skeletal health over the life continuum have not been established. This is partly due to the difficulty in quantifying the effects of variable levels of a nutrient’s intake over a lifetime as well as the complex nature of the relationships between dietary protein and calcium economy. Areas of current uncertainty include the precise source and amount of dietary protein required for optimal skeletal accretion and maintenance of skeletal mass, as well as the site-specific effects of dietary protein. The cellular and molecular mechanisms that underpin the actions of dietary protein on mineral metabolism and skeletal homeostasis remain unclear. This review attempts to summarize recent data bearing on these questions.
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影响因子：
4
作者：
Dawson-Hughes, B.;Harris, S. S.;Dallal, G. E.
通讯作者：
Dallal, G. E.
DOI：
10.1615/critreveukaryotgeneexpr.v9.i1.30
发表时间：
1999-01-01
影响因子：
1.6
作者：
Bonewald, LF
通讯作者：
Bonewald, LF
影响因子：
6.2
作者：
Chevalley, Thierry;Bonjour, Jean-Philippe;Rizzoli, Rene
通讯作者：
Rizzoli, Rene
影响因子：
7.1
作者：
Hoppe, C;Udam, TR;Michaelsen, KF
通讯作者：
Michaelsen, KF
影响因子：
7.1
作者：
Beasley, Jeannette M.;LaCroix, Andrea Z.;Prentice, Ross L.
通讯作者：
Prentice, Ross L.