Profiling Phospholipids within Atlantic Salmon Salmo salar with Regards to a Novel Terrestrial Omega-3 Oil Source.
Profiling Phospholipids within Atlantic Salmon Salmo salar with Regards to a Novel Terrestrial Omega-3 Oil Source.
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DOI：
10.3390/metabo12090851
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发表时间：
2022-09-10
期刊：
影响因子：
4.1
通讯作者：
中科院分区：
文献类型：
--
作者：
开发和列入新的油从转基因（GM）油籽到水产饲料，以补充和取代目前的陆地油籽，以及鱼油，值得更彻底的调查脂质生化改变鱼类物种，如大西洋鲑鱼。在两个收获时间点检查了五种组织，以确定是否可以在标准商业饮食与包含来自转基因油菜籽亚麻荠的长链多不饱和脂肪酸（LC-PUFA）、EPA（二十碳五烯酸）和DHA（二十二碳六烯酸）的饮食之间检测到脂质异构体变化。检测到组织依赖性趋势，表明某些器官，如大脑，具有LC-PUFA掺入的基础限制，尽管这些脂肪酸的富集是可能的。还检测到脂质酰基改变以及推定的立体特异性编号（sn）异构体改变，这提供了转基因油可以改变脂质结构的证据，其中感兴趣的脂质提供了一组靶向标记，通过这些标记可以在各种新型饮食中监测脂质改变。
The development and inclusion of novel oils derived from genetically modified (GM) oilseeds into aquafeeds, to supplement and supplant current terrestrial oilseeds, as well as fish oils, warrants a more thorough investigation into lipid biochemical alterations within finfish species, such as Atlantic salmon. Five tissues were examined across two harvesting timepoints to establish whether lipid isomeric alterations could be detected between a standard commercial diet versus a diet that incorporated the long-chain polyunsaturated fatty acids (LC-PUFA), EPA (eicosapentaenoic acid), and DHA (docosahexaenoic acid), derived from the GM oilseed Camelina sativa. Tissue-dependent trends were detected, indicating that certain organs, such as the brain, have a basal limit to LC-PUFA incorporation, though enrichment of these fatty acids is possible. Lipid acyl alterations, as well as putative stereospecific numbering (sn) isomer alterations, were also detected, providing evidence that GM oils may modify lipid structure, with lipids of interest providing a set of targeted markers by which lipid alterations can be monitored across various novel diets.
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DOI：
10.1073/pnas.042698699
发表时间：
2002-03-05
影响因子：
11.1
作者：
Kitajka, K;Puskás, LG;Farkas, T
通讯作者：
Farkas, T
DOI：
10.1073/pnas.1512110112
发表时间：
2015-09-29
影响因子：
11.1
作者：
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影响因子：
8.8
作者：
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影响因子：
5.4
作者：
Ruiz-Lopez N;Stubhaug I;Ipharraguerre I;Rimbach G;Menoyo D
通讯作者：
Menoyo D
影响因子：
4.5
作者：
Betancor, M. B.;Sprague, M.;Sayanova, O.;Usher, S.;Campbell, P. J.;Napier, J. A.;Caballero, M. J.;Tocher, D. R.
通讯作者：
Tocher, D. R.