The relationship between mental health and risk of active tuberculosis: a systematic review.
The relationship between mental health and risk of active tuberculosis: a systematic review.
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DOI：
10.1136/bmjopen-2021-048945
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发表时间：
2022-01-06
期刊：
影响因子：
2.9
通讯作者：
Friedland JS
中科院分区：
文献类型：
--
作者：
Hayward SE;Deal A;Rustage K;Nellums LB;Sweetland AC;Boccia D;Hargreaves S;Friedland JS
结核病和精神疾病在全球范围内高度流行，并且经常共存。虽然已知精神健康状况不佳会调节免疫功能，但精神障碍是否在结核病发病率中发挥因果作用尚不清楚。这篇系统性综述研究了心理健康与结核病风险之间的关系，为临床和公共卫生措施提供信息。系统性综述，遵循系统性综述和荟萃分析（PRISMA）指南的首选报告项目。检索MEDLINE、PsycINFO和PsycEXTRA数据库以及参考文献列表和引文检索。入选标准是1970年1月1日至2020年5月11日发表的原始研究，报告了心理健康与结核病风险之间的关联数据。数据提取的研究设计和设置，样本特征，精神疾病和结核病的测量，以及结果，包括效果大小或患病率。使用关键评估技能计划（CASP）和横断面研究评估工具（AXIS）清单对研究进行了批判性评估。筛选了50年来发表的1546份记录，结果有10项研究报告了607184人的数据。研究跨越亚洲、南美洲和非洲，包括情绪障碍和精神障碍。来自亚洲队列研究的强有力证据表明，抑郁症和精神分裂症可增加活动性TB的风险，抑郁症的效应估计值范围为HR=1.15（95% CI 1.03 - 1.28）至2.63（95% CI 1.74 - 3.96），精神分裂症的效应估计值范围为HR=1.52（95% CI 1.29 - 1.79）至RR=3.04。这些数据与来自横断面研究的证据一致，例如，在低收入和中等收入国家进行的一项大型调查（n=242 952）报告，与无结核症状的患者相比，有结核症状的患者抑郁发作的OR=3.68（95% CI 3.01至4.50）。患有精神疾病（包括抑郁症和精神分裂症）的人结核病发病率增加，是筛查和治疗的高风险人群。需要对心理健康和结核病进行综合护理，应对心理疾病和潜在驱动因素的干预措施可能有助于降低全球结核病发病率。CRD 42019158071。
Tuberculosis (TB) and mental illnesses are highly prevalent globally and often coexist. While poor mental health is known to modulate immune function, whether mental disorders play a causal role in TB incidence is unknown. This systematic review examines the association between mental health and TB disease risk to inform clinical and public health measures. Systematic review, following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. MEDLINE, PsycINFO and PsycEXTRA databases were searched alongside reference list and citation searching. Inclusion criteria were original research studies published 1 January 1970–11 May 2020 reporting data on the association between mental health and TB risk. Data were extracted on study design and setting, sample characteristics, measurement of mental illness and TB, and outcomes including effect size or prevalence. Studies were critically appraised using Critical Appraisal Skills Programme (CASP) and Appraisal Tool for Cross-Sectional Studies (AXIS) checklists. 1546 records published over 50 years were screened, resulting in 10 studies included reporting data from 607 184 individuals. Studies span across Asia, South America and Africa, and include mood and psychotic disorders. There is robust evidence from cohort studies in Asia demonstrating that depression and schizophrenia can increase risk of active TB, with effect estimates ranging from HR=1.15 (95% CI 1.03 to 1.28) to 2.63 (95% CI 1.74 to 3.96) for depression and HR=1.52 (95% CI 1.29 to 1.79) to RR=3.04 for schizophrenia. These data align with evidence from cross-sectional studies, for example, a large survey across low-income and middle-income countries (n=242 952) reports OR=3.68 (95% CI 3.01 to 4.50) for a depressive episode in those with TB symptoms versus those without. Individuals with mental illnesses including depression and schizophrenia experience increased TB incidence and represent a high-risk population to target for screening and treatment. Integrated care for mental health and TB is needed, and interventions tackling mental illnesses and underlying drivers may help reduce TB incidence globally. CRD42019158071.
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DOI：
10.1016/j.ijtb.2019.02.007
发表时间：
2019-01-01
期刊：
The Indian journal of tuberculosis
影响因子：
--
作者：
Chandra, Mina;Rana, Proteesh;Arora, Vijay Kumar
通讯作者：
Arora, Vijay Kumar
精神障碍对主动结核病治疗结果的影响：系统评价和荟萃分析。
DOI：
10.5588/ijtld.20.0458
发表时间：
2020-12-01
期刊：
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease
影响因子：
--
作者：
Lee G;Scuffell J;Galea JT;Shin SS;Magill E;Jaramillo E;Sweetland AC
通讯作者：
Sweetland AC
影响因子：
4.5
作者：
Loennroth, Knut;Williams, Brian G.;Stadlin, Stephanie;Jaramillo, Ernesto;Dye, Christopher
通讯作者：
Dye, Christopher
DOI：
10.1086/594126
发表时间：
2009-01-01
期刊：
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
影响因子：
--
作者：
Deiss RG;Rodwell TC;Garfein RS
通讯作者：
Garfein RS
DOI：
10.1016/j.socscimed.2010.04.027
发表时间：
2010-08
期刊：
Social science & medicine (1982)
影响因子：
--
作者：
Lund C;Breen A;Flisher AJ;Kakuma R;Corrigall J;Joska JA;Swartz L;Patel V
通讯作者：
Patel V