The Association between Mercury and Lead Exposure and Liver and Kidney Function in Pregnant Surinamese Women Enrolled in the Caribbean Consortium for Research in Environmental and Occupational Health (CCREOH) Environmental Epidemiologic Cohort Study.
The Association between Mercury and Lead Exposure and Liver and Kidney Function in Pregnant Surinamese Women Enrolled in the Caribbean Consortium for Research in Environmental and Occupational Health (CCREOH) Environmental Epidemiologic Cohort Study.
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DOI：
10.3390/toxics10100584
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发表时间：
2022-10-04
期刊：
影响因子：
4.6
通讯作者：
Zijlmans W
中科院分区：
文献类型：
--
作者：
Kort SAR;Wickliffe J;Shankar A;Shafer M;Hindori-Mohangoo AD;Covert HH;Lichtveld M;Zijlmans W
接触汞（Hg）和铅（Pb）可能会对孕妇产生影响。我们评估了汞和铅暴露对参与加勒比环境和职业健康研究联合会（CREOH）-Meki Tamara研究的孕妇子队列的肝脏和肾脏功能的影响。从400名年龄在16-46岁的妇女生活在农村，城市和内陆地区的苏里南，我们测量了血汞和血铅水平。测量肌酐、尿素和胱抑素C以评估肾功能，测量天冬氨酸氨基转移酶（AST）、丙氨酸氨基转移酶（ALT）和γ-谷氨酰转移酶（GGT）以评估肝功能。教育、地区和种族在血汞和血铅水平方面存在显著差异，p值均< 0.001。血汞水平越高，肌酐和尿素水平越高。我们的研究结果还表明，高汞血液水平与对肝脏和肾脏功能的潜在有害影响之间存在关系。
Exposure to mercury (Hg) and lead (Pb) may have an effect on pregnant women. We assessed the effect of exposure to mercury and lead on liver and kidney functions in a subcohort of pregnant women who participated in the Caribbean Consortium for Research in Environmental and Occupational Health (CCREOH)—Meki Tamara, study. From 400 women aged 16–46 living in rural, urban, and interior regions of Suriname, we measured blood mercury and blood lead levels. Creatinine, urea, and cystatin C were measured to assess kidney function, and aspartate amino transferase (AST), alanine amino transferase (ALT), and gamma-glutamyl transferase (GGT) were measured to assess liver function. Education, region, and ethnicity showed significant differences for both blood mercury and lead levels, which all had p-values < 0.001. Creatinine and urea were elevated with higher mercury blood levels. Our findings also suggest a relationship between high mercury blood levels and potential harmful effects on liver and kidney function.
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影响因子：
10.4
作者：
Gibb H;O'Leary KG
通讯作者：
O'Leary KG
影响因子：
8.3
作者：
Barbosa, Fernando, Jr.;Fillion, Myriam;Mergler, Donna
通讯作者：
Mergler, Donna
影响因子：
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作者：
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通讯作者：
Curban, Gary C.
DOI：
10.3390/ijerph18084174
发表时间：
2021-04-15
影响因子：
--
作者：
Kuraeiad S;Kotepui M
通讯作者：
Kotepui M
DOI：
10.1007/s00420-010-0522-6
发表时间：
2011-01-01
影响因子：
3
作者：
Kim, Nam-Soo;Lee, Byung-Kook
通讯作者：
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