Sequence of changes in rat buccal mucosa induced by zinc deficiency.
Sequence of changes in rat buccal mucosa induced by zinc deficiency.
复制标题
缺锌引起的大鼠颊粘膜的变化序列。
DOI:
10.1111/j.1600-0714.1991.tb00436.x
复制
发表时间:
1991
期刊:
影响因子:
--
通讯作者:
Daniel,J
中科院分区:
文献类型:
--
作者:
Hsu,D;Meyer,J;Gerson,S;Daniel,J
In weanling rats, after receiving a zinc‐deficient diet (<1 ppm) for 4 wk, the buccal mucosa appears hyperplastic. This study determines changes at earlier stages of the lesion. After 9 days of deficiency, the keratin layer had partially converted to parakeratosis and thickened, and the size of the capillary bed was increased. After 18 days, the keratin layer was fully parakeratotic and thickened further. The cellular layer was thickened. The mitotic rate was doubled and rate ridges were convoluted. After 27 days, the keratin and cellular layers were further thickened, and the mitotic rate remained elevated. The rate ridges were further convoluted. The number of mast cells was doubled and the size of the vascular bed had increased further. These findings suggest early and late interactions between the epithelium and lamina propria. After four days on a control diet following 27 days of zinc deficiency, the mucosa returned normal.
登录
查看更多内容
DOI:
10.1111/1523-1747.ep13077211
发表时间:
1972
期刊:
The Journal of investigative dermatology
影响因子:
--
作者:
K. Nishioka;T. Ryan
通讯作者:
T. Ryan
DOI:
10.1111/1523-1747.ep12676198
发表时间:
1973-09
期刊:
The Journal of investigative dermatology
影响因子:
--
作者:
J. Wolf;R. Harrison
通讯作者:
J. Wolf;R. Harrison
DOI:
--
发表时间:
1973
期刊:
Journal of oral pathology
影响因子:
--
作者:
O. Alvares;J. Meyer
通讯作者:
J. Meyer
影响因子:
3
作者:
Stablein,M;Meyer,J
通讯作者:
Meyer,J
DOI:
--
发表时间:
1981
期刊:
影响因子:
--
作者:
Julia Meyer;M. R. Stohle;M. Stablein
通讯作者:
M. Stablein