Prevalence of use of non-prescription analgesics in the Norwegian HUNT3 population: Impact of gender, age, exercise and prescription of opioids.
Prevalence of use of non-prescription analgesics in the Norwegian HUNT3 population: Impact of gender, age, exercise and prescription of opioids.
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在挪威Hunt3人群中使用非处方镇痛药的使用率：性别，年龄，运动和处方阿片类药物的影响。
DOI：
10.1186/s12889-015-1774-6
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发表时间：
2015-05-02
影响因子：
4.5
通讯作者：
Skurtveit S
中科院分区：
文献类型：
--
作者：
Dale O;Borchgrevink PC;Fredheim OM;Mahic M;Romundstad P;Skurtveit S
人们担心非处方止痛药的使用可能会增加。本研究的目的是检查1）自我报告使用OTC镇痛药的患病率; 2）处方镇痛药与OTC镇痛药联合使用的患病率; 3）生活方式因素（如体力活动）是否与每日OTC镇痛药使用的患病率相关。来自Nord-Trøndelag健康研究（HUNT 3，2006-08）的问卷数据，其中包括来自40 000名成年受访者的数据。调查问卷包括关于OTC止痛药使用、社会经济状况、健康相关行为、症状和疾病的问题。数据与挪威处方数据库中的个体数据相关联。采用logistic回归分析研究了不同因素与慢性疼痛和非慢性疼痛患者每日使用对乙酰氨基酚和/或非甾体抗炎药（NSAID）之间的相关性。最近一个月每周至少使用一次OTC镇痛药的患病率为47%。对乙酰氨基酚的使用率几乎为40%，而NSAID和乙酰水杨酸（阿萨）的使用率分别为19%和8%。虽然NSAID的使用随着年龄的增长而减少，阿萨的使用随着年龄的增长而增加，但对乙酰氨基酚的消耗不受年龄的影响。总体而言，更多的女性使用OTC镇痛药。约3-5%使用OTC镇痛药的受试者似乎将这些药物与处方上的相同镇痛药联合收割机联合使用。在报告慢性疼痛的受试者中，OTC镇痛药使用的患病率几乎是无慢性疼痛受试者的两倍。体力活动少的受试者每日使用OTC的风险是体力活动受试者的1.5-4倍。非处方止痛药的使用很普遍，与慢性疼痛、女性和缺乏身体活动有关。
There are concerns about potential increasing use of over-the-counter (OTC) analgesics. The aims of this study were to examine 1) the prevalence of self-reported use of OTC analgesics; 2) the prevalence of combining prescription analgesics drugs with OTC analgesics and 3) whether lifestyle factors such as physical activity were associated with prevalence of daily OTC analgesic use. Questionnaire data from the Nord–Trøndelag health study (HUNT3, 2006–08), which includes data from 40,000 adult respondents. The questionnaire included questions on use of OTC analgesics, socioeconomic conditions, health related behaviour, symptoms and diseases. Data were linked to individual data from the Norwegian Prescription Database. A logistic regression was used to investigate the association between different factors and daily use of paracetamol and/or non-steroid anti-inflammatory drugs (NSAIDs) in patients with and without chronic pain. The prevalence of using OTC analgesics at least once per week in the last month was 47%. Prevalence of paracetamol use was almost 40%, compared to 19% and 8% for NSAIDs and acetylsalicylic acid (ASA), respectively. While the use of NSAIDs decreased and the use of ASA increased with age, paracetamol consumption was unaffected by age. Overall more women used OTC analgesics. About 3-5% of subjects using OTC analgesics appeared to combine these with the same analgesic on prescription. Among subjects reporting chronic pain the prevalence of OTC analgesic use was almost twice as high as among subjects without chronic pain. Subjects with little physical activity had 1.5-4 times greater risk of daily use of OTC compared to physically active subjects. Use of OTC analgesics is prevalent, related to chronic pain, female gender and physical inactivity.
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影响因子：
5.4
作者：
Antonov, K;Isacson, D
通讯作者：
Isacson, D
影响因子：
3.6
作者：
Svendsen, K.;Skurtveit, S.;Fredheim, O. M. S.
通讯作者：
Fredheim, O. M. S.
影响因子：
4
作者：
Kurtze, Nanna;Rangul, Vegar;Hustvedt, Bo-Egil
通讯作者：
Hustvedt, Bo-Egil
影响因子：
7.4
作者：
Turunen, JHO;Mäntyselkä, PT;Ahonen, RS
通讯作者：
Ahonen, RS
影响因子：
7.2
作者：
EGGEN, AE
通讯作者：
EGGEN, AE