Short-term changes of choroidal vascular structures after phacoemulsification surgery.
Short-term changes of choroidal vascular structures after phacoemulsification surgery.
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超声乳化手术后脉络膜血管结构的短期变化
DOI：
10.1186/s12886-018-0749-7
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发表时间：
2018-03-23
影响因子：
2
通讯作者：
Wang J
中科院分区：
文献类型：
--
作者：
Chen H;Wu Z;Chen Y;He M;Wang J
目的探讨白内障超声乳化术后脉络膜血管结构的变化。对36例（36眼）顺利完成超声乳化白内障吸除术的患者进行自身对照研究。术前、术后7天（D7）、1个月（M1）和3个月（M3）通过增强深度成像（EDI）光学相干断层扫描（OCT）扫描获取脉络膜图像。脉络膜血管指数（CVI）被用来评估脉络膜的血管状态，使用图像二值化的Niblack方法。采用配对t检验比较术后平均CVI值与基线值。进行单因素和多元线性回归分析，以确定CVI和其他因素之间的关联。招募患者的平均年龄为63.1 ± 6.9岁。基线时的平均CVI为60.1 ± 5.5%。术后，D7时CVI显著增加至61.7 ± 5.3%，M1时为63.6 ± 4.4%，M3时为64.8 ± 4.0%（分别为p = 0.035、0.0006、< 0.0001）。单因素和多元回归分析显示，CVI与术前中心凹下脉络膜厚度（SFCT）呈正相关，与年龄、眼轴长度（AL）、眼压（IOP）和性别在所有时间点均无显著相关性。超声乳化术导致白内障患者的CVI增加。评价术后CVI的长期变化，可为研究超声乳化与脉络膜病变的关系提供有价值的信息。
To evaluate the changes of choroidal vascular structures in patients after phacoemulsification surgery. A self-control study was conducted on 36 eyes of 36 patients who had uneventful phacoemulsification. Choroidal images were acquired preoperatively, 7 days (D7), 1 month (M1), and 3 months (M3) after surgery from enhanced depth imaging (EDI) optical coherence tomography (OCT) scans. Choroidal vascularity index (CVI) was used to assess vascular status of the choroid using image binarization by the Niblack method. The postoperative values of mean CVI were compared with baseline by paired t-test. Univariate and multiple linear regression analyses were performed to determine the associations between CVI and other factors. The mean age of the recruited patients was 63.1 ± 6.9 years. The mean CVI at baseline was 60.1 ± 5.5%. After surgery, the CVI significantly increased to 61.7 ± 5.3% at D7, 63.6 ± 4.4% at M1 and 64.8 ± 4.0% at M3 (p = 0.035, 0.0006, < 0.0001, respectively). Univariate and multiple regression analysis revealed a positive association between CVI and subfoveal choroidal thickness (SFCT) at pre-operation and no significant association with age, axial length (AL), intraocular pressure (IOP) and gender at all timepoints. Phacoemulsification induced increased CVI in patients diagnosed with cataract. Evaluation of the long-term change of CVI following surgery may provide valuable information for studying the relationship between phacoemulsification and disorders of the choroid.
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