Removal and dispersal of biofluid films by powered medical devices: Modeling infectious agent spreading in dentistry.
Removal and dispersal of biofluid films by powered medical devices: Modeling infectious agent spreading in dentistry.
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DOI：
10.1016/j.isci.2021.103344
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发表时间：
2021-11-19
期刊：
影响因子：
5.8
通讯作者：
Moeendarbary E
中科院分区：
文献类型：
--
作者：
Eames I;D'Aiuto F;Shahreza S;Javanmardi Y;Balachandran R;Hyde M;Ng YL;Gulabivala K;Watson S;Davies H;Szita N;Khajeh J;Suvan J;Moeendarbary E
医疗程序可以分散传染源并传播疾病。特别是，牙科手术可能会带来很高的疾病传播风险，因为它们使用在口腔内操作的高性能仪器，而这些仪器可能含有传染性微生物群或病毒。在这里，我们评估了动力牙科设备去除生物流体膜的能力，并确定了机械力、流体动力和空气动力作为去除和分散过程的主要基础机制。我们的结果表明，在牙科器械与粘附的生物流体膜接触后，潜在的感染因子可以立即被去除和分散，而由于源的去除和冷却水的稀释，其分散程度迅速减弱。我们发现，高速钻头相互作用产生的液滴通常以弹道方式传播，而充满气溶胶的空气往往以水流的形式流过表面。我们的机制研究为减少侵入性医疗过程中感染的传播提供了合理的途径。机械力、水动力和空气动力驱动去除/驱散过程 空气转子具有最高的去除和驱散传染性病原体的能力 气溶胶云以电流形式流动并不断沉降 操纵流体的流变特性可以抑制气溶胶的产生治疗程序；应用物理学
Medical procedures can disperse infectious agents and spread disease. Particularly, dental procedures may pose a high risk of disease transmission as they use high-powered instruments operating within the oral cavity that may contain infectious microbiota or viruses. Here we assess the ability of powered dental devices in removing the biofluid films and identified mechanical, hydrodynamic, and aerodynamic forces as the main underlying mechanisms of removal and dispersal processes. Our results indicate that potentially infectious agents can be removed and dispersed immediately after dental instrument engagement with the adherent biofluid film, while the degree of their dispersal is rapidly depleted owing to the removal of the source and dilution by the coolant water. We found that droplets created by high-speed drill interactions typically travel ballistically, while aerosol-laden air tends to flow as a current over surfaces. Our mechanistic investigation offers plausible routes for reducing the spread of infection during invasive medical procedures. Mechanical, hydrodynamic, and aerodynamic forces drive removal/dispersal processes The air-rotor has the highest ability to remove and disperse infectious agents The aerosol cloud flows as a current and continuously settles Manipulating rheological properties of the fluids can suppress aerosol generation Dentistry; Therapeutic procedure; Applied physics
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DOI：
10.1016/j.jhin.2006.05.022
发表时间：
2006-10
期刊：
The Journal of hospital infection
影响因子：
--
作者：
Tang JW;Li Y;Eames I;Chan PK;Ridgway GL
通讯作者：
Ridgway GL
影响因子：
4.4
作者：
Holliday R;Allison JR;Currie CC;Edwards DC;Bowes C;Pickering K;Reay S;Durham J;Lumb J;Rostami N;Coulter J;Nile C;Jakubovics N
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Jakubovics N
影响因子：
2.4
作者：
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通讯作者：
Liu, Jianping
影响因子：
4.6
作者：
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通讯作者：
Yarin, Alexander L.
DOI：
10.1073/pnas.2012156117
发表时间：
2020-10-13
影响因子：
11.1
作者：
Abkarian, Manouk;Mendez, Simon;Stone, Howard A.
通讯作者：
Stone, Howard A.