Factors involved in the aerosol transmission of infection and control of ventilation in healthcare premises.

Factors involved in the aerosol transmission of infection and control of ventilation in healthcare premises.
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DOI:
10.1016/j.jhin.2006.05.022
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发表时间:
2006-10
期刊:
The Journal of hospital infection
影响因子:
--
通讯作者:
Ridgway GL
Ridgway GL
中科院分区:
其他
文献类型:
--
作者:
Tang JW;Li Y;Eames I;Chan PK;Ridgway GL

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2003年的严重急性呼吸系统综合症(SARS)流行突出了短距离和远距离传播途径,即在受感染的病人和保健工作者之间以及在遥远的地点之间。对于肺结核、麻疹和水痘等其他传染病,气溶胶传播的概念已被广泛接受,因此隔离这类患者是一种规范。随着当前对可能接近的流感大流行的担忧,控制通过传染性空气的传播变得更加重要。因此,本综述的目的是描述涉及以下因素:(1)感染性气溶胶的产生,(2)来自该气溶胶的感染性液滴或液滴核的传播,以及(3)易感宿主吸入此类液滴或液滴核的可能性。在此基础上,提出建议,以改善控制气溶胶传播的感染在医院以及在未来的隔离设施的设计和建设。
The epidemics of severe acute respiratory syndrome (SARS) in 2003 highlighted both short- and long-range transmission routes, i.e. between infected patients and healthcare workers, and between distant locations. With other infections such as tuberculosis, measles and chickenpox, the concept of aerosol transmission is so well accepted that isolation of such patients is the norm. With current concerns about a possible approaching influenza pandemic, the control of transmission via infectious air has become more important. Therefore, the aim of this review is to describe the factors involved in: (1) the generation of an infectious aerosol, (2) the transmission of infectious droplets or droplet nuclei from this aerosol, and (3) the potential for inhalation of such droplets or droplet nuclei by a susceptible host. On this basis, recommendations are made to improve the control of aerosol-transmitted infections in hospitals as well as in the design and construction of future isolation facilities.
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