Digital barcodes of suspension array using laser induced breakdown spectroscopy.
Digital barcodes of suspension array using laser induced breakdown spectroscopy.
复制标题
使用激光诱导击穿光谱的悬浮阵列数字条形码
DOI:
10.1038/srep36511
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发表时间:
2016-11-03
影响因子:
4.6
通讯作者:
Shen Z
中科院分区:
文献类型:
--
作者:
He Q;Liu Y;He Y;Zhu L;Zhang Y;Shen Z
We show a coding method of suspension array based on the laser induced breakdown spectroscopy (LIBS), which promotes the barcodes from analog to digital. As the foundation of digital optical barcodes, nanocrystals encoded microspheres are prepared with self-assembly encapsulation method. We confirm that digital multiplexing of LIBS-based coding method becomes feasible since the microsphere can be coded with direct read-out data of wavelengths, and the method can avoid fluorescence signal crosstalk between barcodes and analyte tags, which lead to overall advantages in accuracy and stability to current fluorescent multicolor coding method. This demonstration increases the capability of multiplexed detection and accurate filtrating, expanding more extensive applications of suspension array in life science.
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