The Rapid Naming Test: Development and initial validation in typically aging adults.
The Rapid Naming Test: Development and initial validation in typically aging adults.
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DOI：
10.1080/13854046.2021.1900399
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发表时间：
2022-10
期刊：
影响因子：
--
通讯作者：
Kramer JH
中科院分区：
文献类型：
--
作者：
Stiver J;Staffaroni AM;Walters SM;You MY;Casaletto KB;Erlhoff SJ;Possin KL;Lukic S;La Joie R;Rabinovici GD;Zimmerman ME;Gorno-Tempini ML;Kramer JH
进行性找字困难是健康老年人的主要认知主诉，也是病理性衰老的一种症状。然而，经典的视觉对抗命名方法在健康的老年人中显示出天花板效应。为了满足对与年龄相关的微妙的单词发现能力下降敏感的命名测试的需求，我们开发了快速命名测试（RNT），这是一种计算机化的、一分钟的快速视觉命名测试。功能完整的老年人（n=145）和年轻人（n=69）完成了RNT。老年人亚群还完成了神经心理测试、功能衰退自我报告量表、淀粉样蛋白-β PET成像和重复RNT给药，以确定测试-重测可靠性。RNT分数呈正态分布，具有良好的重测信度。年轻人比老年人表现得更好。在老年人中，得分越低，年龄越大。较高的分数与语言、处理速度、情景学习和记忆相关。得分与视觉空间或工作记忆测试无关。较差的表现与主观语言能力下降有关，即使在控制了经典命名测试和速度之后也是如此。RNT也与淀粉样蛋白-β负相关。RNT似乎是一个可靠的测试，它对细微的、与年龄相关的单词发现能力下降很敏感。收敛效度和发散效度由其与依赖于视觉命名过程的措施的特定关联所支持。生态效度与主观现实世界语言困难的关系为其提供了支持。最后，较差的表现与淀粉样蛋白-β沉积有关，淀粉样蛋白-β沉积是阿尔茨海默病的生物标志物。这项研究代表了在典型的老年人中验证一种新颖、敏感的命名测试的关键一步。
Progressive word-finding difficulty is a primary cognitive complaint among healthy older adults and a symptom of pathological aging. Classic measures of visual confrontation naming, however, show ceiling effects among healthy older adults. To address the need for a naming test that is sensitive to subtle, age-related word-finding decline, we developed the Rapid Naming Test (RNT), a computerized, one-minute, speeded visual naming test. Functionally intact older (n=145) and younger (n=69) adults completed the RNT. Subsets of older adults also completed neuropsychological tests, a self-report scale of functional decline, amyloid-β PET imaging, and repeat RNT administration to determine test-retest reliability. RNT scores were normally distributed and exhibited good test-retest reliability. Younger adults performed better than older adults. Within older adults, lower scores were associated with older age. Higher scores correlated with measures of language, processing speed, and episodic learning and memory. Scores were not correlated with visuospatial or working memory tests. Worse performance was related to subjective language decline, even after controlling for a classic naming test and speed. The RNT was also negatively associated with amyloid-β burden. The RNT appears to be a reliable test that is sensitive to subtle, age-related word-finding decline. Convergent and divergent validity are supported by its specific associations with measures relying on visual naming processes. Ecological validity is supported by its relationship with subjective real-world language difficulties. Lastly, worse performance was related to amyloid-β deposition, an Alzheimer’s disease biomarker. This study represents a key step toward validating a novel, sensitive naming test in typically aging adults.
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影响因子：
2.4
作者：
Heflin, Lara H.;Laluz, Victor;Jang, Jung;Ketelle, Robin;Miller, Bruce L.;Kramer, Joel H.
通讯作者：
Kramer, Joel H.
影响因子：
8.2
作者：
Hartshorne JK;Germine LT
通讯作者：
Germine LT
影响因子：
3.7
作者：
Brodeur MB;Dionne-Dostie E;Montreuil T;Lepage M
通讯作者：
Lepage M
影响因子：
4
作者：
Facal, David;Juncos-Rabadan, Onesimo;Pereiro, Arturo X.
通讯作者：
Pereiro, Arturo X.
影响因子：
3.7
作者：
Brodeur MB;Guérard K;Bouras M
通讯作者：
Bouras M