Murine typhus in Austin, Texas, USA, 2008.

Murine typhus in Austin, Texas, USA, 2008.
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DOI:
10.3201/eid1603.091028
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发表时间:
2010-03
影响因子:
11.8
通讯作者:
Taylor J
Taylor J
中科院分区:
医学2区
文献类型:
--
作者:
Adjemian J;Parks S;McElroy K;Campbell J;Eremeeva ME;Nicholson WL;McQuiston J;Taylor J

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医生应该警惕这方面的可能情况。2008年8月,德克萨斯州当局和疾病控制和预防中心调查了奥斯汀发热性皮疹疾病数量增加的报告,以确认病原体为伤寒立克次体,评估爆发规模和疾病严重程度,并确定可能导致疾病出现的潜在动物宿主和围产期因素。确定了33例确诊的鼠斑疹伤寒人间病例。据报告,发病时间为3月至10月。无患者死亡,但23例(70%)住院治疗。病例患者在地理上聚集在奥斯汀市中心; 12人(36%)居住在一个邮政编码区。对来自病例-患者家庭附近的野生动物和家畜的标本进行了评估; 18%的猫、44%的狗和71%的负鼠具有对R反应的抗体。伤寒。没有R的证据。在所测试的全血、组织或节肢动物样本中检测到伤寒。这些发现表明,一个R。涉及负鼠和家畜的伤寒循环可能存在于奥斯汀。
Physicians should be alert for possible cases in this area. In August 2008, Texas authorities and the Centers for Disease Control and Prevention investigated reports of increased numbers of febrile rash illnesses in Austin to confirm the causative agent as Rickettsia typhi, to assess the outbreak magnitude and illness severity, and to identify potential animal reservoirs and peridomestic factors that may have contributed to disease emergence. Thirty-three human cases of confirmed murine typhus were identified. Illness onset was reported from March to October. No patients died, but 23 (70%) were hospitalized. The case-patients clustered geographically in central Austin; 12 (36%) resided in a single ZIP code area. Specimens from wildlife and domestic animals near case-patient homes were assessed; 18% of cats, 44% of dogs, and 71% of opossums had antibodies reactive to R. typhi. No evidence of R. typhi was detected in the whole blood, tissue, or arthropod specimens tested. These findings suggest that an R. typhi cycle involving opossums and domestic animals may be present in Austin.
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发表时间: 1997-07-01
影响因子: 11.8
作者:
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发表时间: 2008-10-01
影响因子: 11.8
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