Prevalence Rates and Risk Factors for Primary Open Angle Glaucoma in the Middle East.
Prevalence Rates and Risk Factors for Primary Open Angle Glaucoma in the Middle East.
复制标题
DOI：
10.18502/jovr.v16i4.9755
复制
发表时间：
2021-10
影响因子：
2
通讯作者：
Vercellin ACV
中科院分区：
文献类型：
--
作者：
Torabi R;Harris A;Siesky B;Zukerman R;Oddone F;Mathew S;Januleviciene I;Vercellin ACV
青光眼是一种多因素疾病，是全球不可逆性失明的主要原因。目前的数据已经证明了原发性开角型青光眼（POAG）在欧洲、非洲、西班牙和东亚血统患者中的大致分布。然而，关于POAG在中东（ME）人群中的患病率，文献中存在显著差距。目前的研究基于欧洲模型估计ME POAG患病率。在此，我们使用关键词筛选了65篇关于原发性开角型青光眼ME患病率和特定风险因素的文献：“青光眼”、“患病率”、“发病率”、“风险因素”、“中东”、“中东”、“波斯”、“远东”，以及通过PubMed、Embase、奥维德、Scopus、和Trip搜索，以及2021年3月1日之前发表的相关文章的额外参考列表搜索。在排除了15项具有低统计学把握度、混杂共病眼科疾病和资助偏倚的研究后，纳入了50项合格记录。本系统性综述纳入了ME青光眼风险因素的研究，包括染色体、家族趋势、年龄/性别、社会经济地位、生活方式、眼内压、血管影响、视盘出血、杯盘比、血压、阻塞性睡眠呼吸暂停和糖尿病。我们得出结论，原发性开角型青光眼在ME的患病率可能高于欧洲模型所建议的患病率，ME特异性危险因素可能起作用。然而，这些研究结果受到ME人群水平数据缺乏的严重限制。最终需要设计良好的、具有严格纳入和排除标准的基于人群的纵向研究，以准确评估ME人群中青光眼的流行病学和特定机制风险因素。
Glaucoma is a multifactorial disease and a leading cause of irreversible blindness worldwide. Current data has demonstrated the approximate distribution of primary open-angle glaucoma (POAG) in patients of European, African, Hispanic, and Eastern Asian descent. However, a significant gap in the literature exists regarding the prevalence of POAG in Middle Eastern (ME) populations. Current studies estimate ME POAG prevalence based on a European model. Herein we screened 65 total publications on ME prevalence of POAG and specific risk factors using keywords: “glaucoma”, “prevalence”, “incidence”, “risk factor”, “Middle East”, “Mideast”, “Persian”, “Far East”, as well as searching by individual ME countries through PubMed, Embase, Ovid, Scopus, and Trip searches with additional reference list searches from relevant articles published up to and including March 1, 2021. Fifty qualifying records were included after 15 studies identified with low statistical power, confounding co-morbid ophthalmic diseases, and funding bias were excluded. Studies of ME glaucoma risk factors that identify chromosomes, familial trend, age/gender, socioeconomic status, lifestyle, intraocular pressure, vascular influences, optic disc hemorrhage, cup-to-disc ratio, blood pressure, obstructive sleep apnea, and diabetes mellitus were included in this systematic review. We conclude that the prevalence of POAG in the ME is likely higher than the prevalence rate that European models suggest, with ME specific risk factors likely playing a role. However, these findings are severely limited by the paucity of population-level data in the ME. Well-designed, longitudinal population-based studies with rigorous inclusion and exclusion criteria are ultimately needed to accurately assess the epidemiology and specific mechanistic risk factors of glaucoma in ME populations.
登录
查看更多内容
影响因子：
1.8
作者：
Kondkar AA;Sultan T;Almobarak FA;Kalantan H;Abu-Amero KK;Al-Obeidan SA
通讯作者：
Al-Obeidan SA
DOI：
10.1016/j.oooo.2018.01.021
发表时间：
2018-09-01
影响因子：
2.9
作者：
Friedlander, Arthur H.;Graves, Lindsay L.;Giaconi, JoAnn A.
通讯作者：
Giaconi, JoAnn A.
影响因子：
--
作者：
Amerasinghe, Nishani;Wong, Tien Y.;Aung, Tin
通讯作者：
Aung, Tin
影响因子：
3.1
作者：
Al-Bahlal A;Khandekar R;Al Rubaie K;Alzahim T;Edward DP;Kozak I
通讯作者：
Kozak I
影响因子：
1.6
作者：
Al-Shaaln, Farhan Fayez;Bakrman, Marwan Abdurrahman;Aljoud, Abdullah Srour
通讯作者：
Aljoud, Abdullah Srour