Effectiveness of Brain Gaming in Older Adults With Cognitive Impairments: A Systematic Review and Meta-Analysis.
Effectiveness of Brain Gaming in Older Adults With Cognitive Impairments: A Systematic Review and Meta-Analysis.
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DOI：
10.1016/j.jamda.2021.05.022
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发表时间：
2021-11
影响因子：
7.6
通讯作者：
Devos H
中科院分区：
文献类型：
--
作者：
Kletzel SL;Sood P;Negm A;Heyn PC;Krishnan S;Machtinger J;Hu X;Devos H
本系统综述和荟萃分析评估了随机临床试验（rct）的证据，这些随机临床试验设计了大脑游戏干预，以改善患有认知障碍的老年人的认知功能，包括轻度认知障碍和痴呆。系统回顾和荟萃分析。数据来源-通过系统检索Medline、Pubmed、PsycINFO、Embase、CINAHL、Web of Science和Cochrane等数据库确定相关随机对照试验（rct）。rct的选择首先基于标题和摘要审查，然后由独立审稿人根据预先定义的资格标准进行全文审查。使用Cochrane RoB工具和漏斗图评估偏倚风险（RoB）。主要结局变量为整体认知功能综合评分。系统评价纳入了来自16项随机对照试验的909名轻度认知障碍或痴呆患者。研究质量一般，RoB评估在参与者和工作人员的盲化方面存在偏倚。漏斗图没有显示发表偏倚的证据。14项随机对照试验的荟萃分析显示，与其他干预措施相比，脑游戏对整体认知功能的影响并不显著（合并SMD = 0.08, 95%可信区间[- 0.24 - 0.41],p = 0.61, I2 = 77%）。同样，在记忆、执行功能、视觉空间技能和语言等认知领域也没有发现明显的效果。这一荟萃分析结果表明，与对照组相比，大脑游戏在认知功能的标准化测试中没有显着改善。由于在样本量、游戏平台、认知状态、研究设计、评估工具和训练处方等方面存在相当大的异质性，我们无法自信地反驳大脑游戏是一种有效的认知障碍老年人认知训练方法的前提。对未来研究的建议也包括在内。
This systematic review and meta-analysis is evaluating the evidence from randomized clinical trials (RCTs) that designed brain gaming interventions to improve cognitive functions of older adults with cognitive impairments, including Mild Cognitive Impairments and Dementia. Systematic review and meta-analysis. N/A N/A Data sources- Relevant randomized control trials (RCTs) were identified by a systematic search of databases including Medline, Pubmed, PsycINFO, Embase, CINAHL, Web of Science, and Cochrane. RCTs were selected first based on title and abstract review, and then on full-text review by independent reviewers using pre-defined eligibility criteria. Risk of Bias (RoB) was assessed using the Cochrane RoB tool and funnel plots. The primary outcome variable was the composite score of global cognitive function. 909 participants with mild cognitive impairment or dementia from 16 RCTs were included in the systematic review. The study quality was modest and the RoB assessment showed bias in blinding the participants and personnel. Funnel plots showed no evidence of publication bias. The meta-analysis of 14 RCTs revealed no superior effect of brain gaming compared to other interventions on global cognitive function (pooled SMD = 0.08, 95% confidence interval [−0.24 – 0.41], p = 0.61, I2 = 77%). Likewise, no superior effects were found on cognitive domains of memory, executive function, visuospatial skills, and language. This meta-analysis findings suggest that brain gaming compared to control group does not show significant improvement in standardized tests of cognitive function. Because of considerable heterogeneity in sample size, gaming platform, cognitive status, study design, assessment tools, and training prescription, we cannot confidently refute the premise that brain gaming is an effective cognitive training approach for older adults with cognitive impairments. Recommendations for future research are included.
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影响因子：
2.1
作者：
Barnes DE;Yaffe K;Belfor N;Jagust WJ;DeCarli C;Reed BR;Kramer JH
通讯作者：
Kramer JH
影响因子：
3.7
作者：
Basak, Chandramallika;Boot, Walter R.;Voss, Michelle W.;Kramer, Arthur F.
通讯作者：
Kramer, Arthur F.
影响因子：
4
作者：
Barban, Francesco;Annicchiarico, Roberta;Caltagirone, Carlo
通讯作者：
Caltagirone, Carlo
影响因子：
17.7
作者：
Hill, Nicole T. M.;Mowszowski, Loren;Lampit, Amit
通讯作者：
Lampit, Amit
DOI：
10.1177/1533317509332624
发表时间：
2009-06-01
影响因子：
3.4
作者：
Eckroth-Bucher, Margie;Siberski, James
通讯作者：
Siberski, James