Determinants of COVID-19 vaccination status and hesitancy among older adults in China.
Determinants of COVID-19 vaccination status and hesitancy among older adults in China.
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中国老年人 COVID-19 疫苗接种状况和犹豫的决定因素
DOI：
10.1038/s41591-023-02241-7
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发表时间：
2023-03
期刊：
影响因子：
82.9
通讯作者：
Zhao, Yaohui
中科院分区：
文献类型：
--
作者：
Wang, Gewei;Yao, Yao;Wang, Yafeng;Gong, Jinquan;Meng, Qinqin;Wang, Hui;Wang, Wenjin;Chen, Xinxin;Zhao, Yaohui
接种疫苗是预防严重急性呼吸系统综合征冠状病毒2的主要措施，特别是在老年人和慢性病患者中。使用来自中国健康与退休纵向研究（CHARLS）第五波（2021-2022）的12，900名参与者的全国代表性样本，我们检查了中国52岁及以上成年人的2019冠状病毒病（COVID-19）疫苗接种状况和疫苗接种犹豫的决定因素。截至2022年7月/8月，92. 3%的60岁及以上中国人口已接受至少一次COVID-19疫苗接种，88. 6%已完成初级系列接种，72. 4%已接受加强接种。80岁及以上的人的疫苗接种率较低，分别有71.9%和46.7%完成了初级系列和加强注射。该等统计数字代表中国于二零二二年十一月终止零冠状病毒政策前的情况，原因是疫苗接种于二零二二年七月╱八月至十一月期间停滞。多变量回归分析显示，属于最老年龄组（70岁及以上的个体，特别是80岁及以上的个体）以及女性和未婚、居住在城市地区、功能依赖和患有慢性疾病意味着这些个体接种COVID-19疫苗的可能性较小。我们的回归分析结果得到了自我报告的未接种疫苗原因的证实。在中国停止其零冠状病毒政策后，疫苗接种的犹豫可能导致了脆弱人群的死亡率过高。我们的研究为如何平衡遏制措施与疫苗接种和治疗措施提供了重要的经验教训，并强调需要尽早澄清疫苗的副作用和禁忌症。
Vaccination is the primary defense against severe acute respiratory syndrome coronavirus 2, especially among older adults and those with chronic conditions. Using a nationally representative sample of 12,900 participants from the fifth wave (2021–2022) of the China Health and Retirement Longitudinal Study (CHARLS), we examined the coronavirus disease 2019 (COVID-19) vaccination status and the determinants of vaccination hesitancy in Chinese adults aged 52 and older. By July/August 2022, 92.3% of the Chinese population aged 60 years and older had received at least one COVID-19 vaccination, 88.6% had completed the primary series and 72.4% had received a booster. Those aged 80 years and older had lower vaccination rates, with 71.9% and 46.7% completing the primary series and booster shots, respectively. These statistics represent the situation before China ended the Zero-COVID policy in November 2022 because vaccination stagnated between July/August and November 2022. Multivariate regression analysis revealed that belonging to the oldest age groups (individuals aged 70 years and older and especially those aged 80 years and older) as well as being female and unmarried, residing in urban areas, being functionally dependent and having chronic conditions meant that these individuals were less likely to receive COVID-19 vaccines. Our regression analysis results were corroborated by self-reported reasons for nonvaccination. Vaccination hesitancy probably contributed to excessive mortality among vulnerable populations after China ceased its Zero-COVID policy. Our study provides important lessons on how to balance containment efforts with vaccination and treatment measures, as well as highlighting the need to clarify the side effects and contraindications of vaccines early on.
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影响因子：
13.8
作者：
Persad G;Emanuel EJ;Sangenito S;Glickman A;Phillips S;Largent EA
通讯作者：
Largent EA
DOI：
10.1016/s2468-2667(21)00012-8
发表时间：
2021-04
期刊：
The Lancet. Public health
影响因子：
--
作者：
Schwarzinger M;Watson V;Arwidson P;Alla F;Luchini S
通讯作者：
Luchini S
影响因子：
6.9
作者：
Freeman D;Lambe S;Yu LM;Freeman J;Chadwick A;Vaccari C;Waite F;Rosebrock L;Petit A;Vanderslott S;Lewandowsky S;Larkin M;Innocenti S;McShane H;Pollard AJ;Loe BS
通讯作者：
Loe BS
影响因子：
5.5
作者：
Hou, Zhiyuan;Guo, Jia;Fang, Hai
通讯作者：
Fang, Hai
影响因子：
5.5
作者：
Luk TT;Zhao S;Wu Y;Wong JY;Wang MP;Lam TH
通讯作者：
Lam TH