Depression and Handgrip Strength Among U.S. Adults Aged 60 Years and Older from NHANES 2011-2014.
Depression and Handgrip Strength Among U.S. Adults Aged 60 Years and Older from NHANES 2011-2014.
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DOI：
10.1007/s12603-018-1041-5
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发表时间：
2018
期刊：
影响因子：
--
通讯作者：
Batsis JA
中科院分区：
文献类型：
--
作者：
Brooks JM;Titus AJ;Bruce ML;Orzechowski NM;Mackenzie TA;Bartels SJ;Batsis JA
肌肉减少症是随着年龄增长而发生的肌肉质量和力量的逐渐丧失。这种肌肉退化与发病率增加，残疾和其他不良后果有关。虽然减少的握力可以被认为是老年人肌肉减少症和其他衰老相关下降的标志，但在具有常见生物心理社会条件（如抑郁症）的高危人群中，对这种身体健康问题的研究有限。我们的主要目标是确定60岁及以上成年人的综合握力水平及其与抑郁症的关系。未调整和调整的线性回归模型进行了横断面调查数据集。2011-2014年国家健康和营养检查调查（NHANES）的次要数据集。社区居住、非机构化成人≥ 60岁（n= 3，421）。预测变量包括临床相关抑郁症的阳性筛选（参考=PHQ-9评分<10）。使用测力计确定联合握力（kg）的标准变量。平均年龄和BMI分别为69.9岁（51.5%为女性）和28.8 kg/m2。在整个队列中，男性和女性的平均综合握力分别为73.5和46.6 kg。336人（9.8%）报告了抑郁症状。在未校正和完全校正的模型中，抑郁与握力降低显著相关（分别为B =-0.26 ±0.79和B =-0.19 ±0.08; p<0.001）。我们的研究结果表明，握力与抑郁症有显着的负相关。未来的纵向研究应调查抑郁症和握力降低之间的关系的因果过程和潜在的调节剂和调解员。这些信息可能会进一步鼓励使用抑郁和握力评估，并有助于监测和实施解决老年人身心健康限制的医疗保健服务。
Sarcopenia is a gradual loss of muscle mass and strength that occurs with aging. This muscle deterioration is linked to increased morbidity, disability, and other adverse outcomes. Although reduced handgrip strength can be considered a marker of sarcopenia and other aging-related decline in the elderly, there is limited research on this physical health problem in at-risk groups with common biopsychosocial conditions such as depression. Our primary objective was to ascertain level of combined handgrip strength and its relationship with depression among adults aged 60 years and older. Unadjusted and adjusted linear regression models were conducted with a cross-sectional survey dataset. Secondary dataset from the 2011–2014 National Health and Nutrition Examination Survey (NHANES). Community-dwelling, non-institutionalized adults ≥ 60 years old (n=3,421). The predictor variables included a positive screen for clinically relevant depression (referent=PHQ-9 score <10). The criterion variable of combined handgrip strength (kg) was determined using a dynamometer. Mean age and BMI were 69.9 years (51.5% female) and 28.8 kg/m2, respectively. Mean combined handgrip strength in the overall cohort was 73.5 and 46.6 kg in males and females, respectively. Three hundred thirty-six (9.8%) reported symptoms of depression. In unadjusted and fully adjusted models, depression was significantly associated with reduced handgrip strength (B = −0.26±0.79 and B = −0.19±0.08, respectively; p<0.001). Our findings demonstrate handgrip strength has a significant inverse association with depression. Future longitudinal studies should investigate the causal processes and potential moderators and mediators of the relationships between depression and reduced handgrip strength. This information may further encourage the use of depression and handgrip strength assessments and aid in the monitoring and implementation of health care services that address both physical and mental health limitations among older adult populations.
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影响因子：
--
作者：
Kim TN;Choi KM
通讯作者：
Choi KM
影响因子：
4.7
作者：
Batsis, J. A.;Mackenzie, T. A.;Bartels, S. J.
通讯作者：
Bartels, S. J.
DOI：
10.1016/j.nutres.2015.09.003
发表时间：
2015-12
期刊：
Nutrition research (New York, N.Y.)
影响因子：
--
作者：
Batsis JA;Mackenzie TA;Lopez-Jimenez F;Bartels SJ
通讯作者：
Bartels SJ
影响因子：
4.1
作者：
Beck, AT;Brown, GK;Grisham, J
通讯作者：
Grisham, J
DOI：
10.1016/j.jamda.2013.03.019
发表时间：
2013-07-01
影响因子：
7.6
作者：
Lee, Wei-Ju;Liu, Li-Kuo;Chen, Liang-Kung
通讯作者：
Chen, Liang-Kung