Uterine natural killer cells: To protect and to nurture.
Uterine natural killer cells: To protect and to nurture.
复制标题
子宫自然杀伤细胞:保护和培育。
DOI:
10.1002/bdr2.1419
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发表时间:
2018-12-01
影响因子:
2.1
通讯作者:
Yokoyama WM
中科院分区:
文献类型:
--
作者:
Sojka DK;Yang L;Yokoyama WM
During the course of pregnancy, the maternal-fetal interface is tightly regulated and undergoes dynamic changes that promote the successful development of the semi-allogeneic fetus. In response to embryo implantation, the uterus remodels with maternal immune cells occupying the maternal-fetal interface and uterine natural killer (uNK) cells becoming the most prominent leukocyte. Recently, uNK cells have been discovered to be heterogeneous, including conventional NK (cNK) and tissue-resident NK (trNK) cells. Here, we will review the recent advances in uNK cell biology and discuss their functional mechanisms which protect and nurture the growing fetus.
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影响因子:
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通讯作者:
Ashkar, AAA
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通讯作者:
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影响因子:
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通讯作者:
WIGZELL, H