Comparison of Mandibular Phenotypic and Genetic Integration between Baboon and Mouse.
Comparison of Mandibular Phenotypic and Genetic Integration between Baboon and Mouse.
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DOI：
10.1007/s11692-009-9056-9
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发表时间：
2009-03
影响因子：
2.5
通讯作者：
Richtsmeier, Joan T.
中科院分区：
文献类型：
--
作者：
Willmore, Katherine E.;Roseman, Charles C.;Rogers, Jeffrey;Cheverud, James M.;Richtsmeier, Joan T.
在这项研究中，我们比较了小鼠和狒狒之间的下颌骨整合的模式，使用表型和定量遗传数据。具体来说，我们测试如何以及每个物种适合与镶嵌模型的下颌骨整合建议的Atchley和霍尔（生物学评论坎布Philos Soc 66：101-157，1991年）的基础上发展模块。我们假设，整合的模式将是相似的小鼠和狒狒，这两个物种将显示出强大的整合内的发展模块和较弱的模块之间的整合。相应的地标数据收集先进的intercross小鼠样本（N = 1239）和下颌骨的狒狒样本的已知谱系从西南基金会生物医学研究（N = 430）的半下颌骨。我们使用了四种分析方法来量化和比较不同物种之间下颌骨整合的程度，包括两种基于先验假设的方法和两种后验分析。我们发现，狒狒和小鼠下颌骨的整合模式大致相似，这两个物种都显示出模块化的整合模式。虽然有一个总的趋势，物种之间的整合模式的相似性，有一些显着的差异。小鼠的冠状突和切牙齿槽区域内的距离之间有很强的相关性，而狒狒的髁突内强烈整合。我们讨论了潜在的进化影响，这些物种之间的整合模式相似，强调模块化的作用。
In this study we compare patterns of mandibular integration between mice and baboons using both phenotypic and quantitative genetic data. Specifically, we test how well each species fits with the mosaic model of mandibular integration suggested by Atchley and Hall (Biol Rev Camb Philos Soc 66:101–157, 1991) based on developmental modules. We hypothesize that patterns of integration will be similar for mice and baboons and that both species will show strong integration within developmental modules and weaker integration between modules. Corresponding landmark data were collected from the hemi-mandibles of an advanced intercross mouse sample (N = 1239) and mandibles from a baboon sample of known pedigree from the Southwest Foundation for Biomedical Research (N = 430). We used four methods of analysis to quantify and compare the degree of mandibular integration between species including two methods based on a priori assumptions, and two a posteriori analyses. We found that patterns of integration are broadly similar for baboon and mouse mandibles, with both species displaying a modular pattern of integration. While there is a general trend of similarity in integration patterns between species, there were some marked differences. Mice are strongly correlated among distances within the coronoid process and the incisive alveolar region, whereas baboons are strongly integrated within the condylar process. We discuss the potential evolutionary implications of the similar patterns of integration between these species with an emphasis on the role of modularity.
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影响因子：
1.5
作者：
HYLANDER, WL
通讯作者：
HYLANDER, WL
影响因子：
3.3
作者：
BERG, RL
通讯作者：
BERG, RL
影响因子：
2.9
作者：
Goswami, Anjali
通讯作者：
Goswami, Anjali
影响因子：
3.3
作者：
CHEVERUD, JM
通讯作者：
CHEVERUD, JM
DOI：
10.1002/jez.b.00009
发表时间：
2003-04-15
影响因子：
2.2
作者：
Ehrich, TH;Vaughn, TT;Cheverud, JM
通讯作者：
Cheverud, JM