Evolving gene expression: from G to E to GxE.
Evolving gene expression: from G to E to GxE.
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DOI:
10.1016/j.tree.2009.06.011
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发表时间:
2009-12
影响因子:
16.8
通讯作者:
Townsend JP
中科院分区:
文献类型:
--
作者:
Hodgins-Davis A;Townsend JP
Analyses of gene expression datasets from multiple individuals and species promise to illuminate the mode of evolution of gene expression. However, complementary complexities challenge this enterprise. Characterization of the genetic variation underlying gene expression can easily be compromised by lack of environmental control. Conversely, the breadth of conclusions from studies of environmental effects have been limited by use of single strains. Controlled studies have hinted at extensive gene-by-environment interaction. Thus, both genetics and environment are key components to models of the evolution of gene expression. We review the literature on the genetics of gene expression evolution (G), the environmental response literature (E), and the literature on gene expression as a G x E interaction to make this conceptual point.
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