OrthoDB: the hierarchical catalog of eukaryotic orthologs.
OrthoDB: the hierarchical catalog of eukaryotic orthologs.
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Orthodb:真核直系同源物的分层目录。
DOI:
10.1093/nar/gkm845
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发表时间:
2008-01
影响因子:
14.9
通讯作者:
Zdobnov, Evgeny M.
中科院分区:
文献类型:
--
作者:
Kriventseva, Evgenia V.;Rahman, Nazim;Espinosa, Octavio;Zdobnov, Evgeny M.
The concept of orthology is widely used to relate genes across different species using comparative genomics, and it provides the basis for inferring gene function. Here we present the web accessible OrthoDB database that catalogs groups of orthologous genes in a hierarchical manner, at each radiation of the species phylogeny, from more general groups to more fine-grained delineations between closely related species. We used a COG-like and Inparanoid-like ortholog delineation procedure on the basis of all-against-all Smith-Waterman sequence comparisons to analyze 58 eukaryotic genomes, focusing on vertebrates, insects and fungi to facilitate further comparative studies. The database is freely available at http://cegg.unige.ch/orthodb
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影响因子:
14.9
作者:
Li, Heng;Coghlan, Avril;Ruan, Jue;Coin, Lachlan James;Heriche, Jean-Karim;Osmotherly, Lara;Li, Ruiqiang;Liu, Tao;Zhang, Zhang;Bolund, Lars;Wong, Gane Ka-Shu;Zheng, Weimou;Dehal, Paramvir;Wang, Jun;Durbin, Richard
通讯作者:
Durbin, Richard
DOI:
10.1073/pnas.89.22.10915
发表时间:
1992-11-15
影响因子:
11.1
作者:
HENIKOFF, S;HENIKOFF, JG
通讯作者:
HENIKOFF, JG
影响因子:
14.9
作者:
DURET, L;MOUCHIROUD, D;GOUY, M
通讯作者:
GOUY, M
影响因子:
3.2
作者:
JONES, CH;TATTI, KM;MORAN, CP
通讯作者:
MORAN, CP
影响因子:
11.4
作者:
Zdobnov, Evgeny M.;Bork, Peer
通讯作者:
Bork, Peer