Long-term health impacts of COVID-19 among 242,712 adults in England.
Long-term health impacts of COVID-19 among 242,712 adults in England.
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DOI：
10.1038/s41467-023-41879-2
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发表时间：
2023-10-24
影响因子：
16.6
通讯作者：
Elliott, Paul
中科院分区：
文献类型：
--
作者：
Atchison, Christina J.;Davies, Bethan;Cooper, Emily;Lound, Adam;Whitaker, Matthew;Hampshire, Adam;Azor, Adriana;Donnelly, Christl A.;Chadeau-Hyam, Marc;Cooke, Graham S.;Ward, Helen;Elliott, Paul
COVID-19大流行对健康及福祉造成持续影响。我们比较了COVID-19后症状持续的人与从未检测出SARS-CoV-2感染阳性的人以及从COVID-19中康复的人目前自我报告的健康状况、生活质量和症状特征。总的来说，276，840/800，000（34.6%）的受邀参与者参加了会议。与从未患过COVID-19或已康复的参与者相比，在COVID后持续存在症状的参与者的心理健康和健康相关生活质量更差。在这项研究中，COVID相关症状的中位持续时间（N = 130，251）为1.3周（四分位数范围为6天至2周），分别有7.5%和5.2%的患者报告持续症状≥12周和≥52周。女性、≥1种合并症和在野生型变异占优势时感染与症状持续≥12周的概率较高以及症状持续的患者恢复时间较长相关。虽然COVID-19通常持续时间很短，但一些成年人会经历持续和沉重的疾病。症状性COVID-19的持续时间及其对健康和生活质量的影响尚不清楚。在这项研究中，作者报告了对英格兰约275，000名成年人的调查结果，发现持续的COVID-19相对罕见，但与心理健康和健康相关的生活质量较差有关。
The COVID-19 pandemic is having a lasting impact on health and well-being. We compare current self-reported health, quality of life and symptom profiles for people with ongoing symptoms following COVID-19 to those who have never tested positive for SARS-CoV-2 infection and those who have recovered from COVID-19. Overall, 276,840/800,000 (34·6%) of invited participants took part. Mental health and health-related quality of life were worse among participants with ongoing persistent symptoms post-COVID compared with those who had never had COVID-19 or had recovered. In this study, median duration of COVID-related symptoms (N = 130,251) was 1·3 weeks (inter-quartile range 6 days to 2 weeks), with 7·5% and 5·2% reporting ongoing symptoms ≥12 weeks and ≥52 weeks respectively. Female sex, ≥1 comorbidity and being infected when Wild-type variant was dominant were associated with higher probability of symptoms lasting ≥12 weeks and longer recovery time in those with persistent symptoms. Although COVID-19 is usually of short duration, some adults experience persistent and burdensome illness. The duration of symptomatic COVID-19 and its impacts on health and quality of life are not well understood. In this study, the authors report results from a survey of ~275,000 adults in England and find that persistent COVID-19 is relatively rare but is associated with poorer mental health and health-related quality of life.
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DOI：
10.1126/science.abn8347
发表时间：
2022-03-25
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Elliott P;Bodinier B;Eales O;Wang H;Haw D;Elliott J;Whitaker M;Jonnerby J;Tang D;Walters CE;Atchison C;Diggle PJ;Page AJ;Trotter AJ;Ashby D;Barclay W;Taylor G;Ward H;Darzi A;Cooke GS;Chadeau-Hyam M;Donnelly CA
通讯作者：
Donnelly CA
COVID-19 的 50 多种长期影响：系统回顾和荟萃分析。
影响因子：
4.6
作者：
Lopez-Leon S;Wegman-Ostrosky T;Perelman C;Sepulveda R;Rebolledo PA;Cuapio A;Villapol S
通讯作者：
Villapol S
DOI：
10.1136/bmjmed-2022-000385
发表时间：
2023
期刊：
BMJ medicine
影响因子：
--
作者：
Byambasuren, Oyungerel;Stehlik, Paulina;Clark, Justin;Alcorn, Kylie;Glasziou, Paul
通讯作者：
Glasziou, Paul
DOI：
10.1016/s2213-2600(21)00383-0
发表时间：
2021-11
期刊：
The Lancet. Respiratory medicine
影响因子：
--
作者：
Evans RA;McAuley H;Harrison EM;Shikotra A;Singapuri A;Sereno M;Elneima O;Docherty AB;Lone NI;Leavy OC;Daines L;Baillie JK;Brown JS;Chalder T;De Soyza A;Diar Bakerly N;Easom N;Geddes JR;Greening NJ;Hart N;Heaney LG;Heller S;Howard L;Hurst JR;Jacob J;Jenkins RG;Jolley C;Kerr S;Kon OM;Lewis K;Lord JM;McCann GP;Neubauer S;Openshaw PJM;Parekh D;Pfeffer P;Rahman NM;Raman B;Richardson M;Rowland M;Semple MG;Shah AM;Singh SJ;Sheikh A;Thomas D;Toshner M;Chalmers JD;Ho LP;Horsley A;Marks M;Poinasamy K;Wain LV;Brightling CE;PHOSP-COVID Collaborative Group
通讯作者：
PHOSP-COVID Collaborative Group
影响因子：
3.8
作者：
Johnson, Sverre Urnes;Ulvenes, Pal Gunnar;Hoffart, Asle
通讯作者：
Hoffart, Asle