Transforming the Concept of Memory Reactivation.

Transforming the Concept of Memory Reactivation.
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DOI:
10.1016/j.tins.2020.09.006
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发表时间:
2020-12
影响因子:
15.9
通讯作者:
Kuhl BA
Kuhl BA
中科院分区:
医学1区
文献类型:
--
作者:
Favila SE;Lee H;Kuhl BA

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重新激活指的是在知觉体验过程中表达的神经活动模式在稍后的时间重新表达的现象--这是一种假定的记忆神经标记。在人类的许多皮层区域观察到知觉内容的重新激活,并与人类记忆的客观和主观表达相关。然而,由于重新激活强调知觉和基于记忆的表征之间的相似之处,它掩盖了感知事件和记忆如何表征的差异。在这里,我们强调最近的证据表明,感知事件和记忆在大脑中的表现方式(以及位置)存在系统性差异。我们认为,记忆的神经表征最好被认为是知觉表征的空间转换版本。我们考虑了为什么会发生空间变化,并为未来的研究确定了关键问题。
Reactivation refers to the phenomenon wherein patterns of neural activity expressed during perceptual experience are re-expressed at a later time—a putative neural marker of memory. Reactivation of perceptual content has been observed across many cortical areas and correlates with objective and subjective expressions of memory in humans. However, because reactivation emphasizes similarities between perceptual and memory-based representations, it obscures differences in how perceptual events and memories are represented. Here, we highlight recent evidence of systematic differences in how (and where) perceptual events and memories are represented in the brain. We argue that neural representations of memories are best thought of as spatially transformed versions of perceptual representations. We consider why spatial transformations occur and identify critical questions for future research.
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