BMI is strongly associated with hypertension, and waist circumference is strongly associated with type 2 diabetes and dyslipidemia, in northern Chinese adults.
BMI is strongly associated with hypertension, and waist circumference is strongly associated with type 2 diabetes and dyslipidemia, in northern Chinese adults.
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在中国北方成年人中，BMI 与高血压密切相关，腰围与 2 型糖尿病和血脂异常密切相关
DOI：
10.2188/jea.je20110120
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发表时间：
2012
影响因子：
4.7
通讯作者：
Li Y
中科院分区：
文献类型：
--
作者：
Feng RN;Zhao C;Wang C;Niu YC;Li K;Guo FC;Li ST;Sun CH;Li Y
背景肥胖与高血压、2型糖尿病(T2 DM)、血脂异常等慢性疾病密切相关。我们分析了代谢综合征(METS)的最佳肥胖指数界值，并在中国北方人群中确定了与这些慢性病更密切相关的肥胖指数。方法对中国北部地区8940名20~74岁成年人进行慢性病调查。受试者操作特征(ROC)分析、相对风险和多元回归被用来为代谢综合征和肥胖相关的慢性疾病制定一个合适的指数和最佳的临界值。结果腰围(WC)和体重指数(BMI)是METS的良好标志，WC是T2 DM和血脂异常的良好标志，BMI是高血压的良好标志。男性和女性的最佳BMI分界值分别为24 kg/m2和86 cm和78 cm。相对危险回归模型显示，BMI与高血压、T2 DM、高甘油三酯血症相关，高血压患病率(PR)为2.35(95%CI，2.18~2.50)。腰围与2型糖尿病、高血压、高甘油三酯血症相关，T2 DM组PR为2.05(1.63~2.55)，高甘油三酯血症组为2.47(2.04~2.85)。在多元回归模型中，SBP和DBP对BMI的标化回归系数(SRC)较大，WC对空腹血糖、负荷后2小时血糖、甘油三酯和总胆固醇的标化回归系数(SRC)较大。结论我们对中国北方人群的分析表明，METS的最佳界值是男性WCs为86 cm，女性为78 cm，男女BMI均为24 kg/m2。BMI与高血压密切相关，而WC与T2 DM及血脂异常密切相关。
Background Obesity is closely associated with chronic diseases such as hypertension, type 2 diabetes mellitus (T2DM), and dyslipidemia. We analyzed the optimal obesity index cut-off values for metabolic syndrome (MetS), and identified the obesity index that is more closely associated with these chronic diseases, in a population of northern Chinese. Methods We surveyed 8940 adults (age, 20–74 years) living in northern China for chronic diseases. Receiver operating characteristics (ROC) analysis, relative risk, and multivariate regression were used to develop an appropriate index and optimal cut-off values for MetS and obesity-related chronic diseases. Results Waist circumference (WC) and body mass index (BMI) were good markers for MetS, WC was a good marker for T2DM and dyslipidemia, and BMI was a good marker for hypertension. The optimal BMI cut-off value of MetS was 24 kg/m2, and the optimal WC cut-offs were 86 cm and 78 cm in men and women, respectively. Relative risk regression models showed that BMI was associated with hypertension, T2DM, and hypertriglyceridemia and a higher prevalence ratio (PR) for hypertension: 2.35 (95% CI, 2.18–2.50). WC was associated with T2DM, hypertension, and hypertriglyceridemia, with PRs of 2.05 (1.63–2.55) for T2DM and 2.47 (2.04–2.85) for hypertriglyceridemia. In multivariate regression models, the standardized regression coefficients (SRCs) of BMI were greater for SBP and DBP, and the SRC of WC was greater for fasting blood glucose, 2-hour postload blood glucose, triglyceride, and total cholesterol. Conclusions Our analysis of a population of northern Chinese indicates that the optimal cut-off values for MetS are WCs of 86 cm in men and 78 cm in women and a BMI of 24 kg/m2 in both sexes. BMI was strongly associated with hypertension, while WC was strongly associated with T2DM and dyslipidemia.
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影响因子：
5
作者：
Baik, I;Ascherio, A;Willett, WC
通讯作者：
Willett, WC
影响因子：
5.6
作者：
Ajani, UA;Lotufo, PA;Manson, JE
通讯作者：
Manson, JE
影响因子：
16.2
作者：
Hara, K;Matsushita, Y;Kadowaki, T
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Kadowaki, T
影响因子：
6.9
作者：
Ko, Gan T. C.;Tang, Joyce S. F.
通讯作者：
Tang, Joyce S. F.
影响因子：
6.9
作者：
Lorenzo, Carlos;Serrano-Rios, Manuel;Haffner, Steven M.
通讯作者：
Haffner, Steven M.