Frequency tuning of the contralateral medial olivocochlear reflex in humans.

Frequency tuning of the contralateral medial olivocochlear reflex in humans.
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人类对侧内侧橄榄耳蜗反射的频率调谐。

DOI:
10.1152/jn.00051.2012
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发表时间:
2012
影响因子:
2.5
通讯作者:
Dhar,Sumitrajit
Dhar,Sumitrajit
中科院分区:
医学3区
文献类型:
--
作者:
Zhao,Wei;Dhar,Sumitrajit

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内侧耳蜗(MOC)传出信号的激活会减弱耳蜗增益,降低耳蜗机械、电和神经输出的振幅。MOC传出神经的功能作用尚不完全清楚,特别是在人类中,尽管假设它们参与保护免受声创伤,促进瞬态声音感知等。描述MOC输出的频率调谐特性将为支持或反驳这些假设的功能角色提供关键证据。通过利用自发耳声发射(SOAE),一种对MOC调制敏感的耳蜗测量,我们系统地证明了人类对侧MOC反射被调谐到500至1,000 Hz之间的固定频段,与SOAE频率无关。我们的研究结果质疑MOC反射在保护听觉创伤或促进瞬态声音感知方面的作用。
Activation of the medial olivocochlear (MOC) efferents attenuates cochlear gain and reduces the amplitudes of mechanical, electrical, and neural cochlear outputs. The functional roles of the MOC efferents are not fully understood, especially in humans, despite postulations that they are involved in protection against acoustic trauma, facilitation of transient-sound perception, etc. Delineating the frequency tuning properties of the MOC efferents would provide critical evidence to support or refute these postulated functional roles. By utilizing spontaneous otoacoustic emissions (SOAEs), a cochlear measure sensitive to MOC modulation, we systematically demonstrate in humans that the contralateral MOC reflex is tuned to a fixed frequency band between 500 and 1,000 Hz independent of SOAE frequency. Our results question the role of the MOC reflex in protection against acoustic trauma or facilitation of transient-sound perception.
交叉橄榄耳蜗束的电刺激对猫单听神经纤维对突发音调反应的影响的变化。
DOI: 10.1121/1.1912235
发表时间: 1970
期刊: The Journal of the Acoustical Society of America
影响因子: --
作者:
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DOI: 10.1152/jn.1956.19.5.424
发表时间: 1956-01-01
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DOI: 10.1016/0378-5955(93)90064-8
发表时间: 1993-06-01
期刊: HEARING RESEARCH
影响因子: 2.8
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DOI: 10.1016/0378-5955(84)90042-x
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期刊: HEARING RESEARCH
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投射到豚鼠耳蜗的传出神经元的脑干位置
DOI: --
发表时间: 1985
期刊: Hearing Research
影响因子: 2.8
作者:
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通讯作者: D. Robertson