A comparison of the histological structure of the placenta in experimental animals.
A comparison of the histological structure of the placenta in experimental animals.
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DOI：
10.1293/tox.2013-0060
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发表时间：
2014-04
影响因子：
1.2
通讯作者：
Sugiyama A
中科院分区：
文献类型：
--
作者：
Furukawa S;Kuroda Y;Sugiyama A
胎盘的主要功能是充当母体和胎儿之间的界面。真兽类哺乳动物绒毛膜尿囊胎盘的解剖结构因不同动物物种而异。真兽类哺乳动物的胎盘类型根据总体形状、母胎界面的组织学结构、母胎交叉的类型等从不同的角度进行分类。特别是，组织学结构通常被认为是功能性描述胎盘类型最有用和最具指导性的分类之一。在该系统中，根据构成间质区域的细胞层识别三种主要类型：（1）上皮绒毛膜类型（马、猪和反刍动物），（2）内皮绒毛膜类型（食肉动物）和（3）血绒毛膜类型（灵长类动物，啮齿动物和兔子）。血管间区域的细胞层数量被认为可以改变母体和胎儿血液之间营养物质的转移，并且是动物物种之间胎盘通透性差异的重要因素之一。因此，在生殖和发育毒性研究中，在推断不同动物物种胎盘转移特征的信息时，应特别注意血管间区域的组织学结构。
The primary function of the placenta is to act as an interface between the dam and fetus. The anatomic structure of the chorioallantoic placenta in eutherian mammals varies between different animal species. The placental types in eutherian mammals are classified from various standpoints based on the gross shape, the histological structure of the materno-fetal interface, the type of materno-fetal interdigitation, etc. Particularly, the histological structure is generally considered one of the most useful and instructive classifications for functionally describing placental type. In this system, three main types are recognized according to the cell layers comprising the interhemal area: (1) epitheliochorial type (horses, pigs and ruminants), (2) endotheliochorial type (carnivores) and (3) hemochorial type (primates, rodents and rabbits). The number of cell layers in the interhemal area is considered to modify the transfer of nutrients between maternal and fetal blood and is one of the important factors with respect to the difference in placental permeability between animal species. Therefore, in reproductive and developmental toxicity studies, careful attention should be paid to the histological structure of the interhemal area when extrapolating information concerning placental transfer characteristics to different animal species.
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影响因子：
4.1
作者：
Bauer, MK;Harding, JE;Gluckman, PD
通讯作者：
Gluckman, PD
DOI：
10.1002/tera.1420410403
发表时间：
1990-04-01
期刊：
TERATOLOGY
影响因子：
--
作者：
JOLLIE, WP
通讯作者：
JOLLIE, WP
DOI：
10.1016/j.vascn.2010.05.009
发表时间：
2010-11-01
影响因子：
1.9
作者：
Bode, Gerd;Clausing, Peter;Sims, Jennifer
通讯作者：
Sims, Jennifer
影响因子：
3.8
作者：
Enders, AC;Carter, AM
通讯作者：
Carter, AM
影响因子：
3.8
作者：
Enders, A. C.;Carter, A. M.
通讯作者：
Carter, A. M.