A Systematic Review of Spiritually Based Interventions and Psychoneuroimmunological Outcomes in Breast Cancer Survivorship.
A Systematic Review of Spiritually Based Interventions and Psychoneuroimmunological Outcomes in Breast Cancer Survivorship.
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DOI：
10.1177/1534735416636222
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发表时间：
2016-12
影响因子：
2.9
通讯作者：
Armer JM
中科院分区：
文献类型：
--
作者：
Hulett JM;Armer JM
目标。这是一个基于精神的干预（例如，正念减压），利用心理神经免疫学（PNI）结果测量乳腺癌幸存者的回顾。具体来说，这篇综述试图检查关于精神干预、心理-社会-精神结果和乳腺癌幸存者生物标志物结果之间关系的证据。方法。系统检索了2005-2015年9个在线数据库的原创研究、同行评议、随机和非随机对照试验的文章。提取数据是为了回答有关精神干预中使用的心理-社会-精神和生理测量之间关系的选定问题。讨论了未来以精神为基础的乳腺癌生存干预的意义。结果。共综述了22篇文章。皮质醇是最常见的PNI生物标志物。与对照组相比，干预组表现出积极的心理健康结果，神经内分泌免疫谱得到改善或稳定，尽管存在局限性。与以前的综述相比，设计方法在增加对照组使用方面有所改进。很少有以精神为基础的干预措施专门衡量宗教或精神结构。同样，很少有现有的研究将标准化的宗教或精神测量与PNI结果测量相结合。研究结果表明，现在存在一个知识体系来支持正念-呼吸-伸展组件的干预；此外，与对照组相比，这些干预措施似乎可以改善或稳定乳腺癌幸存者的神经内分泌免疫活动。结论。从PNI的角度来看，未来基于精神的干预措施应该包括宗教信仰和精神的标准化措施，以便了解宗教信仰、精神和神经内分泌免疫结果之间的关系。未来的研究现在应该集中在确定改善或稳定神经内分泌免疫功能所需的最小剂量和持续时间，以及不同的环境需求，包括对病情严重无法前往小组会议或缺乏经济资源的幸存者进行家庭实践。
Objective. This is a review of spiritually based interventions (eg, mindfulness-based stress reduction) that utilized psychoneuroimmunological (PNI) outcome measures in breast cancer survivors. Specifically, this review sought to examine the evidence regarding relationships between spiritually based interventions, psychosocial-spiritual outcomes, and biomarker outcomes in breast cancer survivors. Methods. A systematic search of 9 online databases was conducted for articles of original research, peer-reviewed, randomized and nonrandomized control trials from 2005-2015. Data were extracted in order to answer selected questions regarding relationships between psychosocial-spiritual and physiological measures utilized in spiritually based interventions. Implications for future spiritually based interventions in breast cancer survivorship are discussed. Results. Twenty-two articles were reviewed. Cortisol was the most common PNI biomarker outcome studied. Compared with control groups, intervention groups demonstrated positive mental health outcomes and improved or stable neuroendocrine-immune profiles, although limitations exist. Design methods have improved with regard to increased use of comparison groups compared with previous reviews. There are few spiritually based interventions that specifically measure religious or spiritual constructs. Similarly, there are few existing studies that utilize standardized religious or spiritual measures with PNI outcome measures. Findings suggest that a body of knowledge now exists in support of interventions with mindfulness-breathing-stretching components; furthermore, these interventions appear to offer potential improvement or stabilization of neuroendocrine-immune activity in breast cancer survivors compared to control groups. Conclusion. From a PNI perspective, future spiritually based interventions should include standardized measures of religiousness and spirituality in order to understand relationships between and among religiousness, spirituality, and neuroendocrine-immune outcomes. Future research should now focus on determining the minimum dose and duration needed to improve or stabilize neuroendocrine-immune function, as well as diverse setting needs, including home-based practice for survivors who are too ill to travel to group sessions or lack economic resources.
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影响因子：
3.7
作者：
Carlson, LE;Speca, M;Goodey, E
通讯作者：
Goodey, E
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3.8
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Bower JE;Greendale G;Crosswell AD;Garet D;Sternlieb B;Ganz PA;Irwin MR;Olmstead R;Arevalo J;Cole SW
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Cole SW