Microstructural Parcellation of the Human Cerebral Cortex - From Brodmann's Post-Mortem Map to in vivo Mapping with High-Field Magnetic Resonance Imaging.

Microstructural Parcellation of the Human Cerebral Cortex - From Brodmann's Post-Mortem Map to in vivo Mapping with High-Field Magnetic Resonance Imaging.
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DOI:
10.3389/fnhum.2011.00019
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发表时间:
2011
影响因子:
2.9
通讯作者:
Turner R
Turner R
中科院分区:
医学3区
文献类型:
--
作者:
Geyer S;Weiss M;Reimann K;Lohmann G;Turner R

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2009年是著名的科尔比安·布罗德曼脑图出版100周年。尽管这是大脑皮层显微解剖学的经典指南,但从当今最先进的神经成像角度来看,使用布罗德曼的地图作为大脑皮层功能单位的结构指南是有问题的。在这篇文章中,我们讨论了其中的一些原因,特别是显微结构脑图的“死后世界”与神经成像的“活体世界”的兼容性问题。最后,我们对活体结构脑成像的未来进行了展望:这是一种新的方法,具有在活体人类大脑的微结构和功能之间建立直接关联的巨大潜力:使用高场磁共振成像的“体内布罗德曼成像”。
The year 2009 marked the 100th anniversary of the publication of the famous brain map of Korbinian Brodmann. Although a “classic” guide to microanatomical parcellation of the cerebral cortex, it is – from today's state-of-the-art neuroimaging perspective – problematic to use Brodmann's map as a structural guide to functional units in the cortex. In this article we discuss some of the reasons, especially the problematic compatibility of the “post-mortem world” of microstructural brain maps with the “in vivo world” of neuroimaging. We conclude with some prospects for the future of in vivo structural brain mapping: a new approach which has the enormous potential to make direct correlations between microstructure and function in living human brains: “in vivo Brodmann mapping” with high-field magnetic resonance imaging.
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