Prevalence of amblyopia and strabismus in white and African American children aged 6 through 71 months the Baltimore Pediatric Eye Disease Study.

Prevalence of amblyopia and strabismus in white and African American children aged 6 through 71 months the Baltimore Pediatric Eye Disease Study.
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DOI:
10.1016/j.ophtha.2009.04.034
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发表时间:
2009-11
期刊:
影响因子:
13.7
通讯作者:
Tielsch JM
Tielsch JM
中科院分区:
医学1区
文献类型:
--
作者:
Friedman DS;Repka MX;Katz J;Giordano L;Ibironke J;Hawse P;Tielsch JM

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确定6 - 71个月白色和非裔美国儿童斜视的年龄特异性患病率以及30 - 71个月白色和非裔美国儿童弱视的年龄特异性患病率。基于人群的横断面研究。美国马里兰州巴尔的摩6至71个月的白色和非洲裔美国儿童。在确认的4,132名儿童中,有3,990名符合条件的儿童(97%)参加了调查,2,546名儿童(62%)接受了检查。合格参与者的父母或监护人进行了家庭访谈,并安排了详细的眼科检查,包括验光视力和眼偏差的测量。斜视被定义为近距离或远距离注视时的斜视。弱视是在那些年龄在30到71个月的儿童中评估的,他们能够在3米处进行视力测试。6 - 71个月斜视儿童和30 - 71个月弱视儿童的比例。在3.3%的白色儿童和2.1%的非裔美国儿童中发现明显斜视(相对患病率(RP)1.61,95%置信区间(CI):0.97,2.66)。内斜视和外斜视各占两组斜视的近一半。在84名6至11个月的白色儿童中,仅发现一例斜视。60 - 71个月儿童的发生率较高(白人为5.8%,非裔美国人为2.9%(RP:2.05,95% CI:0.79,5.27)。12例(1.8%)白色儿童和7例(0.8%)非裔美国儿童存在弱视(RP:2.23,95% CI:0.88,5.62)。只有一个孩子有双眼弱视。在学龄前白色儿童和非裔美国儿童中,显性斜视分别为1/30和1/47。白人和非裔美国人的弱视患病率均低于2%。国家人口预测表明,在美国,6-71个月大的儿童中约有677,000例明显斜视,30-71个月大的儿童中约有271,000例弱视。
To determine the age-specific prevalence of strabismus in White and African-American children aged 6 through 71 months and of amblyopia in White and African-American children aged 30 through 71 months. Cross-sectional population-based study. White and African-American children aged 6 through 71 months in Baltimore, Maryland, United States. Among 4,132 children identified, 3,990 eligible children (97%) were enrolled and 2,546 children (62%) were examined. Parents or guardians of eligible participants underwent an in-home interview and were scheduled for a detailed eye examination including optotype visual acuity and measurement of ocular deviations. Strabismus was defined as a heterotropia at near or distance fixation. Amblyopia was assessed in those children aged 30 through 71 months who were able to perform optotype testing at 3 meters. The proportions of children aged 6 through 71 months with strabismus and of children aged 30 through 71 months with amblyopia. Manifest strabismus was found in 3.3% of White and 2.1% of African American children (relative prevalence (RP) 1.61, 95% confidence interval (CI): 0.97, 2.66). Esotropia and exotropia each accounted for close to half of all strabismus in both groups. Only one case of strabismus was found among 84 White children 6 through 11 months of age. Rates were higher in children 60 through 71 months of age (5.8% for Whites and 2.9% for African Americans (RP: 2.05, 95% CI: 0.79, 5.27). Amblyopia was present in 12 (1.8%) White and 7 (0.8%) African American children (RP: 2.23, 95% CI: 0.88, 5.62). Only one child had bilateral amblyopia. Manifest strabismus affected 1 in 30 White and 1 in 47 African-American preschool aged children. The prevalence of amblyopia was under 2% in both Whites and African-Americans. National population projections suggest that there are approximately 677,000 cases of manifest strabismus among children 6–71 months of age and 271,000 cases of amblyopia among children 30–71 months of age in the United States.
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