Genome-wide Identification, Classification, Molecular Evolution and Expression Analysis of Malate Dehydrogenases in Apple.
Genome-wide Identification, Classification, Molecular Evolution and Expression Analysis of Malate Dehydrogenases in Apple.
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苹果苹果酸脱氢酶的全基因组鉴定、分类、分子进化和表达分析
DOI：
10.3390/ijms19113312
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发表时间：
2018-10-24
影响因子：
5.6
通讯作者：
Ma F
中科院分区：
文献类型：
--
作者：
Ma B;Yuan Y;Gao M;Xing L;Li C;Li M;Ma F
脱氢酶在能量稳态，植物的发育和耐盐和盐的耐受性中起着至关重要的作用，因为它介导了苹果酸的可逆转化率，但是在这项研究中，苹果中MDH基因的进化模式在这项研究中仍然难以捉摸。 mdmdh的效果基因。对MDMDH基因的染色体定位和KA/KS比分析揭示了对重复的MDMDH基因的选择性压力。在苹果水果开发过程中高度表达花芽的分化是正面的。代谢。
Malate dehydrogenase plays crucial roles in energy homeostasis, plant development and cold and salt tolerance, as it mediates the reversible conversion of malate to oxaloacetate. However, the evolutionary pattern of MDH genes in apple remains elusive. In this study, a total of 20 MDH genes were identified from the “Golden Delicious” apple draft genome. We revealed the physiological and biochemical properties, gene structure, and conserved motifs of MdMDH genes. Chromosomal localization and Ka/Ks ratio analysis of MdMDH genes revealed different selective pressures acted on duplicated MdMDH genes. Exploration of the phylogenetic relationships revealed six clades and similar frequencies between old and recent duplications, and significant differences in the evolutionary rates of the MDH gene family were observed. One MdMDH gene, MDP0000807458, which was highly expressed during apple fruit development and flower bud differentiation, was under positive selection. Thus, we speculated that MDP0000807458 is a likely candidate gene involved in regulation of flower bud differentiation and organic acid metabolism in apple fruits. This study provides a foundation for improved understanding of the molecular evolution of MdMDH genes and further facilitates the functional analysis of MDP0000807458 to unravel its exact role in flower bud differentiation and organic acid metabolism.
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影响因子：
13.8
作者：
Wang QJ;Sun H;Dong QL;Sun TY;Jin ZX;Hao YJ;Yao YX
通讯作者：
Yao YX
苹果中铝激活苹果酸转运蛋白的全基因组鉴定、分子进化和表达差异
影响因子：
5.6
作者：
Ma, Baiquan;Yuan, Yangyang;Ma, Fengwang
通讯作者：
Ma, Fengwang
转录组测序和代谢物分析揭示飞燕草素代谢对葡萄风信子花色的作用
影响因子：
6.9
作者：
Lou Q;Liu Y;Qi Y;Jiao S;Tian F;Jiang L;Wang Y
通讯作者：
Wang Y
DOI：
10.1073/pnas.0501102102
发表时间：
2005-04-12
影响因子：
11.1
作者：
Maere, S;De Bodt, S;Van de Peer, Y
通讯作者：
Van de Peer, Y
影响因子：
4.9
作者：
Xing, Li-Bo;Zhang, Dong;Han, Ming-Yu
通讯作者：
Han, Ming-Yu