Biominerals--hierarchical nanocomposites: the example of bone.

Biominerals--hierarchical nanocomposites: the example of bone.
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DOI:
10.1002/wnan.105
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发表时间:
2011-01
影响因子:
8.6
通讯作者:
Beniash, Elia
Beniash, Elia
中科院分区:
医学2区
文献类型:
--
作者:
Beniash, Elia

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许多生物体在其组织中掺入无机固体以增强其功能,主要是机械性质。这些矿化组织,也称为生物矿物,是独特的有机-矿物纳米复合材料,在几个层次上组织,从纳米到宏观尺度。与通常是其组分的简单物理混合物的人造复合材料不同,生物矿物中的有机相和无机相在分子水平上界面。虽然这些组织在环境条件下由相对较弱的组分组成,但它们的分级结构组织和不同元素之间的密切相互作用导致了上级机械性能。了解这些组织的形成,结构和功能特性的基本原理可能会导致新的生物启发的材料设计和更好的治疗矿化组织疾病的策略。本文以骨组织为例,重点介绍了生物矿物的结构组成、形成和功能特性的一般原理。
Many organisms incorporate inorganic solids in their tissues to enhance their functional, primarily mechanical, properties. These mineralized tissues, also called biominerals, are unique organo-mineral nanocomposites, organized at several hierarchical levels, from nano- to macroscale. Unlike man made composite materials, which often are simple physical blends of their components, the organic and inorganic phases in biominerals interface at the molecular level. Although these tissues are made of relatively weak components at ambient conditions, their hierarchical structural organization and intimate interactions between different elements lead to superior mechanical properties. Understanding basic principles of formation, structure and functional properties of these tissues might lead to novel bioinspired strategies for material design and better treatments for diseases of the mineralized tissues. This review focuses on general principles of structural organization, formation and functional properties of biominerals on the example the bone tissues.
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