Selection on the Fly: Short-Term Adaptation to an Altered Sexual Selection Regime in Drosophila pseudoobscura.
Selection on the Fly: Short-Term Adaptation to an Altered Sexual Selection Regime in Drosophila pseudoobscura.
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DOI：
10.1093/gbe/evad113
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发表时间：
2023-07-03
影响因子：
3.3
通讯作者：
Kosiol, Carolin
中科院分区：
文献类型：
--
作者：
Barata, Carolina;Snook, Rhonda R.;Ritchie, Michael G.;Kosiol, Carolin
实验进化研究是研究实验室种群进化历史的有力手段。此类研究揭示了选择如何改变表型和基因型。这些研究中的大多数都没有通过在多个时间点重新测序种群的基因组来研究性选择操纵下的适应时间进程。在这里，我们分析了等位基因频率轨迹在果蝇pseudobscura，我们改变了他们的性选择制度为200代，并在5个时间点测序汇总人口。性选择的强度在一夫一妻制群体（M）中是放松的，在一妻多夫制群体（E）中是升高的。我们对选择如何在染色体和基因水平上改变群体遗传学参数进行了全面研究。我们调查了有效群体大小的差异-治疗之间，并进行全基因组扫描，以确定从时间序列数据选择的签名。我们在D.伪暗在E系中有更显著的变异，正如预期的那样，来自更强的性选择。然而，我们发现在两种处理中，X染色体上的反应都是实质性的，在E中更明显，在M中仅限于最近的性连锁染色体臂XR。在实验进化的第一代中，我们估计E系中的X较低，这可能表明在选择开始时的快速适应反应。此外，第三条染色体受到一妻多夫的影响，其远端含有一个区域，显示出强烈的适应性进化信号，特别是在E系中。
Experimental evolution studies are powerful approaches to examine the evolutionary history of lab populations. Such studies have shed light on how selection changes phenotypes and genotypes. Most of these studies have not examined the time course of adaptation under sexual selection manipulation, by resequencing the populations’ genomes at multiple time points. Here, we analyze allele frequency trajectories in Drosophila pseudoobscura where we altered their sexual selection regime for 200 generations and sequenced pooled populations at 5 time points. The intensity of sexual selection was either relaxed in monogamous populations (M) or elevated in polyandrous lines (E). We present a comprehensive study of how selection alters population genetics parameters at the chromosome and gene level. We investigate differences in the effective population size——between the treatments, and perform a genome-wide scan to identify signatures of selection from the time-series data. We found genomic signatures of adaptation to both regimes in D. pseudoobscura. There are more significant variants in E lines as expected from stronger sexual selection. However, we found that the response on the X chromosome was substantial in both treatments, more pronounced in E and restricted to the more recently sex-linked chromosome arm XR in M. In the first generations of experimental evolution, we estimate to be lower on the X in E lines, which might indicate a swift adaptive response at the onset of selection. Additionally, the third chromosome was affected by elevated polyandry whereby its distal end harbors a region showing a strong signal of adaptive evolution especially in E lines.
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DOI：
10.1534/g3.117.043349
发表时间：
2017-07-05
期刊：
G3 (Bethesda, Md.)
影响因子：
--
作者：
Barghi N;Tobler R;Nolte V;Schlötterer C
通讯作者：
Schlötterer C
影响因子：
2.1
作者：
Crudgington, H. S.;Fellows, S.;Snook, R. R.
通讯作者：
Snook, R. R.
影响因子：
9.2
作者：
Chenoweth, Stephen F.;Appleton, Nicholas C.;Rundle, Howard D.
通讯作者：
Rundle, Howard D.
DOI：
10.4061/2011/214280
发表时间：
2011-01-01
期刊：
International journal of evolutionary biology
影响因子：
--
作者：
Greenspan, Leah;Clark, Andrew G
通讯作者：
Clark, Andrew G
影响因子：
3.3
作者：
Connallon, Tim;Jakubowski, Erin
通讯作者：
Jakubowski, Erin