Targeted thiazole orange derivative with folate: synthesis, fluorescence and in vivo fluorescence imaging.
Targeted thiazole orange derivative with folate: synthesis, fluorescence and in vivo fluorescence imaging.
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含叶酸的靶向噻唑橙衍生物：合成、荧光和体内荧光成像
DOI：
10.3390/molecules15106983
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发表时间：
2010-10-11
期刊：
影响因子：
--
通讯作者：
Zhang B
中科院分区：
文献类型：
--
作者：
Fei X;Gu Y;Wang Y;Meng Q;Zhang B
A Thiazole Orange conjugated with folate derivative was synthesized in two steps. Firstly, folate was coupled with 1-(3-aminopropyl)-4-methylquinolinium bromide to afford folate-methylquinolinium bromide, which then reacted with benzothiazolium to obtain the title folate-conjugated compound. The compound was evaluated by 1H-NMR MS, TG/DTA and fluorescence spectroscopic methods. The title compound could selectively target folate receptor expressing tumors according to the in vivo fluorescence imaging preliminarily performed on nude mice with breast tumors.
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DOI：
10.1073/pnas.071511098
发表时间：
2001-04-10
影响因子：
11.1
作者：
Shah, N;Cerussi, A;Tromberg, B
通讯作者：
Tromberg, B
影响因子：
4.7
作者：
Singh, Prateek;Gupta, Umesh;Jain, Narendra K.
通讯作者：
Jain, Narendra K.
影响因子：
3.5
作者：
Kennedy, MD;Jallad, KN;Low, PS
通讯作者：
Low, PS
影响因子：
--
作者：
Fei, Xuening;Yang, Shaobin;Gu, Yingchun
通讯作者：
Gu, Yingchun
影响因子：
7.4
作者：
ZEN, JM;PATONAY, G
通讯作者：
PATONAY, G