Instrumentation for Hydrogenative Parahydrogen-Based Hyperpolarization Techniques.
Instrumentation for Hydrogenative Parahydrogen-Based Hyperpolarization Techniques.
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DOI：
10.1021/acs.analchem.1c04863
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发表时间：
2022-01-11
影响因子：
7.4
通讯作者：
Hövener JB
中科院分区：
文献类型：
--
作者：
Schmidt AB;Bowers CR;Buckenmaier K;Chekmenev EY;de Maissin H;Eills J;Ellermann F;Glöggler S;Gordon JW;Knecht S;Koptyug IV;Kuhn J;Pravdivtsev AN;Reineri F;Theis T;Them K;Hövener JB
近一个世纪以来，二氢、仲氢 (pH2) 的纠缠、反对称核自旋态的独特性质一直吸引着物理学家、化学家和其他科学家的兴趣。 pH2 在量子力学 1 的早期被用作模型系统，如今用于为火箭和无燃烧汽车提供燃料。 20 世纪 80 年代，pH2 被发现是一种方便且有效的自旋序源，可以将磁共振 (MR) 信号增强几个数量级。 2−4 随着随后用于生物医学 MR 成像 (MRI) 的超极化 (HP) 造影剂 (CA) 的出现，基于 pH2 的超极化方法在采集第一批 HP 13C 体内图像中发挥了重要作用（图 1）。 5, 6 从那时起，pH2 已被证明对于分析研究和基础研究（例如分析和催化化学或单线态自旋态物理学）具有极高的价值。 7− 10 pH2 可以快速生产并易于储存。作为氢的四种（核）自旋态之一，室温下 25% 的 H2 为 pH2，而另外 75% 为正氢 (oH2)，遵循玻尔兹曼分布。然而，在较低温度下，对位分数会增加，直到大约 25 K，此时可获得 100% pH2。虽然使用适当的催化剂可以快速对位富集，但如果不存在催化剂，pH2 可以在室温下保存数小时至数天，而不会造成重大损失。这些独特的特性使 pH2 成为纯旋转顺序的理想宿主，可以轻松生产，方便储存（在加压瓶中），
The unique properties of the entangled, antisymmetric nuclear spin state of dihydrogen, parahydrogen (pH2), has intrigued physicists, chemists, and other scientists for almost a century. pH2 was used as a model system in the early days of quantum mechanics 1 and is used for fueling rockets as well as combustion-free cars today. In the 1980s, pH2 was discovered as a convenient and potent source of spin order, allowing the enhancement of the signals of magnetic resonance (MR) by several orders of magnitude. 2− 4 In the advent of hyperpolarized (HP) contrast agents (CA) for biomedical MR imaging (MRI) that followed, pH2-based hyperpolarization methods played an important role in the acquisition of the first HP 13C in vivo images (Figure 1). 5, 6 Ever since, pH2 has proven to be highly valuable for analytical investigations and fundamental research, eg, in analytical and catalytic chemistry or in the physics of singlet spin states. 7− 10 pH2 can be produced rapidly and stored easily. As one of four (nuclear) spin states of dihydrogen, 25% of H2 at room temperature is pH2, while the other 75% is orthohydrogen (oH2), following the Boltzmann distribution). At lower temperatures, however, the para-fraction increases until at approximately 25 K, where 100% pH2 is obtained. While the para-enrichment is fast using an appropriate catalyst, pH2 can be stored for hours to days at room temperature without significant loss if the catalyst is absent. These unique properties make pH2 an ideal host of pure spin order that can be produced easily, stored conveniently (in a pressurized bottle),
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影响因子：
2.2
作者：
Baer, Sebastien;Lange, Thomas;Hoevener, Jan-Bernd
通讯作者：
Hoevener, Jan-Bernd
DOI：
10.1039/d0cp06281b
发表时间：
2021-01-28
期刊：
Physical chemistry chemical physics : PCCP
影响因子：
--
作者：
Berner S ;Schmidt AB ;Ellermann F ;Korchak S ;Chekmenev EY ;Glöggler S ;von Elverfeldt D ;Hennig J ;Hövener JB
通讯作者：
Hövener JB
影响因子：
3.7
作者：
Ariyasingha, Nuwandi M.;Salnikov, Oleg G.;Chekmenev, Eduard Y.
通讯作者：
Chekmenev, Eduard Y.
DOI：
10.1007/s10334-005-0007-x
发表时间：
2005-11-01
影响因子：
2.3
作者：
Bhattacharya, P;Harris, K;Ross, BD
通讯作者：
Ross, BD
影响因子：
2.3
作者：
Berner, Stephan;Schmidt, Andreas B.;Hoevener, Jan-Bernd
通讯作者：
Hoevener, Jan-Bernd