Recombinational histories of avian infectious bronchitis virus and turkey coronavirus.
Recombinational histories of avian infectious bronchitis virus and turkey coronavirus.
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DOI:
10.1007/s00705-011-1061-5
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发表时间:
2011-10
影响因子:
2.7
通讯作者:
Hughes AL
中科院分区:
文献类型:
--
作者:
Hughes AL
Phylogenetic analysis of complete genomes of the avian coronaviruses avian infectious bronchitis (AIBV) and turkey coronavirus (TCoV) supported the hypothesis that numerous recombination events have occurred between these viruses. Although the two groups of viruses differed markedly in the sequence of the spike protein, the gene (S) encoding this protein showed no evidence of positive selection or of an elevated mutation rate. Rather, the data suggested that recombination events have homogenized the portions of the genome other than the S gene between the two groups of viruses, while continuing to maintain the two distinct, anciently diverged versions of the S gene. The latter hypothesis was supported by a phylogeny of S proteins from representative coronaviruses, in which S proteins of AIBV and TCoV fell in the same clade. The online version of this article (doi:10.1007/s00705-011-1061-5) contains supplementary material, which is available to authorized users.
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