Fusobacterium nucleatum and adverse pregnancy outcomes: Epidemiological and mechanistic evidence.

Fusobacterium nucleatum and adverse pregnancy outcomes: Epidemiological and mechanistic evidence.
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DOI:
10.1016/j.anaerobe.2018.01.008
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发表时间:
2018-04
期刊:
影响因子:
2.3
通讯作者:
Han YW
Han YW
中科院分区:
生物学3区
文献类型:
--
作者:
Vander Haar EL;So J;Gyamfi-Bannerman C;Han YW

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核梭杆菌是一种与牙周病相关的革兰氏阴性口腔厌氧共生菌。具核梭菌与广泛的全身性疾病有关,包括口腔、胃肠、风湿病和血管病变。由于怀孕风险与牙周病有关,因此也有关于牙周病对不良妊娠结果的影响的重要研究。本文综述了具核梭菌在不良妊娠结局中的作用的流行病学和机制证据。
Fusobacterium nucleatum is a Gram-negative anaerobic oral commensal associated with periodontal disease. F. nucleatum has been implicated in a wide spectrum of systemic diseases, including oral, gastrointestinal, rheumatologic, and vascular pathologies. As pregnancy risk has been linked to periodontal disease, there has also been significant research into the effects of periodontal disease on adverse pregnancy outcomes. This article reviews the epidemiological and mechanistic evidence of the role of F. nucleatum in adverse pregnancy outcomes.
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