Exposure to disinfectants (soap or hydrogen peroxide) increases tolerance to permethrin in Anopheles gambiae populations from the city of Yaoundé, Cameroon.
Exposure to disinfectants (soap or hydrogen peroxide) increases tolerance to permethrin in Anopheles gambiae populations from the city of Yaoundé, Cameroon.
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DOI：
10.1186/1475-2875-13-296
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发表时间：
2014-08-03
期刊：
影响因子：
3
通讯作者：
Awono-Ambene P
中科院分区：
文献类型：
--
作者：
Antonio-Nkondjio C;Youmsi-Goupeyou M;Kopya E;Tene-Fossog B;Njiokou F;Costantini C;Awono-Ambene P
杀虫剂抗药性的迅速扩大限制了疟疾病媒控制干预措施的效率。然而，目前对拟除虫菊酯耐药性诱导因素的认识仍不完整。在本研究中，选择在幼虫阶段的消毒剂，如肥皂和过氧化氢（H2 O2），对成蚊抗性氯菊酯的作用进行了研究。将野外冈比亚按蚊幼虫暴露于不同浓度的肥皂和H2 O2中。在24小时后存活至急性毒性试验的幼虫被饲养至成虫阶段并暴露于氯菊酯。将成人的易感性水平与未处理的对照组进行比较。肥皂或过氧化氢的选择对幼虫发育的长度和羽化率的影响进行了评估。幼虫生物测定分析表明，与肥皂相比，过氧化氢对蚊子幼虫的影响更严重。描述剂量死亡率曲线的回归线显示，过氧化氢的平均值和方差高于肥皂。与对照组相比，幼虫发育持续时间（<5天）和成虫羽化率（1 - 77%）较短且较低。冈比亚按蚊存活到用肥皂或过氧化氢或两者选择的幼虫产生的成虫对氯菊酯的抗性比来自未处理对照组的蚊子高8倍。目前的研究表明，选择压力施加的非杀虫化合物，如肥皂和过氧化氢影响安。冈比亚有限公司对拟除虫菊酯的耐受性。这需要进一步的研究方面的适应安。冈比亚公司到撒哈拉以南非洲城市的污染栖息地。
The rapid expansion of insecticide resistance is limiting the efficiency of malaria vector control interventions. However, current knowledge of factors inducing pyrethroid resistance remains incomplete. In the present study, the role of selection at the larval stage by disinfectants, such as soap and hydrogen peroxide (H2O2), on adult mosquito resistance to permethrin was investigated. Field Anopheles gambiae sensu lato larvae, were exposed to variable concentrations of soap and H2O2. Larvae surviving to acute toxicity assays after 24 hours were reared to the adult stage and exposed to permethrin. The susceptibility level of adults was compared to the untreated control group. The effect of soap or hydrogen peroxide selection on the length of larval development and emergence rate was assessed. Larval bioassays analysis showed a more acute effect of hydrogen peroxide on mosquito larvae compared to soap. The regression lines describing the dose mortality profile showed higher mean and variance to hydrogen peroxide than to soap. The duration of larval development (<5 days) and adults emergence rates (1 to 77%) were shorter and lower compare to control. Anopheles gambiae s.l. larvae surviving to selection with either soap or hydrogen peroxide or both, produced adults who were up to eight-times more resistant to permethrin than mosquitoes from the untreated control group. The present study shows that selective pressure exerted by non-insecticidal compounds such as soap and hydrogen peroxide affect An. gambiae s.l. tolerance to pyrethroids. This requires further studies with regard to the adaptation of An. gambiae s.l. to polluted habitats across sub-Saharan Africa cities.
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影响因子：
--
作者：
Tene Fossog B;Antonio-Nkondjio C;Kengne P;Njiokou F;Besansky NJ;Costantini C
通讯作者：
Costantini C
影响因子：
1.4
作者：
Allinghi, Armando;Calcagno, Graciela;Vilardi, Juan Cesar
通讯作者：
Vilardi, Juan Cesar
影响因子：
3.8
作者：
Poupardin, Rodolphe;Reynaud, Stephane;David, Jean-Philippe
通讯作者：
David, Jean-Philippe
DOI：
10.1017/s1742758406658955
发表时间：
2006-12-01
影响因子：
1.2
作者：
Mireji, Paul Odhiambo;Keating, Joseph;Beier, John
通讯作者：
Beier, John
影响因子：
1.9
作者：
Patil, NS;Lole, KS;Deobagkar, DN
通讯作者：
Deobagkar, DN