Stress Varies Along the Social Density Continuum.

Stress Varies Along the Social Density Continuum.
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DOI:
10.3389/fnsys.2020.582985
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发表时间:
2020
影响因子:
3
通讯作者:
Zelikowsky M
Zelikowsky M
中科院分区:
医学3区
文献类型:
--
作者:
Love J;Zelikowsky M

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社会压力在群居动物的生活中无处不在。虽然重要的研究旨在了解特定的社会互动所带来的具体形式的压力,但很少注意了解社会互动的存在和规模所产生的压力的行为影响和神经基础。然而,在人类和啮齿动物中,长期低和长期高的社会互动率与一系列心理健康问题有关,这表明需要进一步研究。在这里,我们回顾文献研究与不断变化的社会密度相关的行为和神经生物学的研究结果,重点研究慢性社会隔离和慢性社会拥挤的啮齿动物模型,并综合研究结果的背景下,社会密度的连续性,可以经历的社会动物。通过这种综合,我们的目标是总结该领域的现状,并为未来的研究描述有希望的途径,更清楚地定义社会互动对哺乳动物大脑和行为的广泛影响。
Social stress is ubiquitous in the lives of social animals. While significant research has aimed to understand the specific forms of stress imparted by particular social interactions, less attention has been paid to understanding the behavioral effects and neural underpinnings of stress produced by the presence and magnitude of social interactions. However, in humans and rodents alike, chronically low and chronically high rates of social interaction are associated with a suite of mental health issues, suggesting the need for further research. Here, we review literature examining the behavioral and neurobiological findings associated with changing social density, focusing on research on chronic social isolation and chronic social crowding in rodent models, and synthesize findings in the context of the continuum of social density that can be experienced by social animals. Through this synthesis, we aim to both summarize the state of the field and describe promising avenues for future research that would more clearly define the broad effects of social interaction on the brain and behavior in mammals.
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