The physiological basis and measurement of heart rate variability in humans.

The physiological basis and measurement of heart rate variability in humans.
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DOI:
10.1186/s40101-016-0113-7
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发表时间:
2016-09-28
影响因子:
3.1
通讯作者:
Taylor JA
Taylor JA
中科院分区:
医学4区
文献类型:
--
作者:
Draghici AE;Taylor JA

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心血管变异性在250多年前就被认识到了,但直到最近20年才开始认识到其明显的实用性。技术进步已经允许精确测量和量化的短期心血管波动,但是,我们的理解的综合机制,这些振荡的基础是不够的,他们的广泛应用。两个自主分支,副交感神经和交感神经系统,是这些自发心血管波动幅度的关键决定因素。心率变异性可以是个体心血管状况的指标。在这篇综述中,我们将讨论心率波形复杂性的两个主要节律振荡。第一次振荡发生在几个心动周期内,与呼吸有关,称为呼吸性窦性心律失常。第二次振荡发生在大约10 s的周期。由于心血管振荡控制系统的闭环性质,很难定义心血管变量之间的特定关系。在这篇综述中,我们将提出的前馈和反馈机制的基础上的振荡和它们的含义作为定量措施的自主循环控制。我们还将审查各种评估方法。
Cardiovascular variabilities were recognized over 250 years ago, but only in the past 20 years has their apparent utility come to be appreciated. Technological advancement has allowed precise measurement and quantification of short-term cardiovascular fluctuations; however, our understanding of the integrated mechanisms which underlie these oscillations is inadequate for their widespread application. Both autonomic branches, the parasympathetic and sympathetic nervous system, are key determinants of the magnitude of these spontaneous cardiovascular fluctuations. Heart rate variability can be an indicator of an individual cardiovascular condition. In this review, we will discuss the two primary rhythmic oscillations that underlie the complexity of the heart rate waveform. The first oscillation occurs over several cardiac cycles, is respiratory related, and termed respiratory sinus arrhythmia. The second oscillation occurs at an approximate 10 s cycle. Due to the closed-loop nature of the control system of cardiovascular oscillations, it is difficult to define specific relations among cardiovascular variables. In this review, we will present the feedforward and feedback mechanism that underlie both oscillations and their implication as quantitative measures of autonomic circulatory control. We will also review the various methodologies to assess them.
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