Dietary vitamin D intake and prevalence of depressive symptoms during pregnancy in Japan.
Dietary vitamin D intake and prevalence of depressive symptoms during pregnancy in Japan.
复制标题
日本膳食维生素 D 摄入量和妊娠期间抑郁症状的患病率。
DOI：
10.1016/j.nut.2014.06.013
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发表时间：
2015
期刊：
影响因子：
--
通讯作者：
Arakawa M.
中科院分区：
文献类型：
--
作者：
Miyake Y;Tanaka K;Okubo H;Sasaki S;Arakawa M.
虽然维生素D水平和抑郁症状之间的关系已经被探索，但结果并不一致。关于膳食维生素D摄入量与妊娠期抑郁症状之间关系的流行病学证据尚不存在。目前的横断面研究的目的是研究这个问题在Japanes.MethodsThe研究包括1745名孕妇。当女性的流行病学研究中心抑郁量表评分为16分或更高时，抑郁症状被定义为存在。在前一个月的饮食摄入量进行了评估，使用自我管理的饮食史问卷。调整年龄，妊娠，居住地区，儿童数量，家庭结构，抑郁症史，抑郁症家族史，吸烟，二手烟暴露在家里和工作，工作类型，家庭收入，教育，体重指数，饱和脂肪酸的摄入量，和摄入的二十碳五烯酸加二十二碳六烯酸。较高的膳食维生素D摄入量与妊娠期抑郁症状的发生率较低显著相关，独立于潜在的膳食和非膳食混杂因素。多变量优势比在维生素D摄入量的第一、第二、第三和第四分位数中，妊娠期抑郁症状的95%置信区间分别为1（参考），0.79（0.55-1.11）、0.73（0.49-1.07）和0.52（0.30-0.89），分别（趋势P = 0.02）。一项在日本进行的部分研究表明，较高的维生素D摄入量可能与怀孕期间抑郁症状的发病率较低有关。
ObjectiveAlthough the relationship between vitamin D levels and depressive symptoms has been explored, the results are inconsistent. Epidemiologic evidence concerning the relationship between dietary vitamin D intake and depressive symptoms in pregnancy is nonexistent. The aim of this current cross-sectional study was to examine this issue in Japan.MethodsThe study included 1745 pregnant women. Depressive symptoms were defined as present when women had a Center for Epidemiologic Studies Depression Scale score of 16 or higher. Dietary intake during the preceding month was assessed using a self-administered diet history questionnaire. Adjustment was made for age, gestation, region of residence, number of children, family structure, history of depression, family history of depression, smoking, secondhand smoke exposure at home and at work, job type, household income, education, body mass index, intake of saturated fatty acids, and intake of eicosapentaenoic acid plus docosahexaenoic acid.ResultsThe prevalence of depressive symptoms during pregnancy was 19.3%. Higher dietary vitamin D intake was significantly associated with a lower prevalence of depressive symptoms during pregnancy, independent of potential dietary and nondietary confounding factors. Multivariate odds ratios (95% confidence intervals) for depressive symptoms during pregnancy in the first, second, third, and fourth quartiles of assessed intake of vitamin D were 1 (reference), 0.79 (0.55–1.11), 0.73 (0.49–1.07), and 0.52 (0.30–0.89), respectively (Pfor trend = 0.02).ConclusionThe current cross-sectional study in Japan suggests that higher vitamin D intake may be associated with a lower prevalence of depressive symptoms during pregnancy.
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