Effect of multicomponent exercise in cognitive impairment: a systematic review and meta-analysis.
Effect of multicomponent exercise in cognitive impairment: a systematic review and meta-analysis.
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多组分运动对认知障碍的影响：系统回顾和荟萃分析。
DOI：
10.1186/s12877-022-03302-1
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发表时间：
2022-07-25
期刊：
影响因子：
4.1
通讯作者：
Alvarez-Bueno, Celia
中科院分区：
文献类型：
--
作者：
Carlos Venegas-Sanabria, Luis;Cavero-Redondo, Ivan;Martinez-Vizcaino, Vicente;Alberto Cano-Gutierrez, Carlos;Alvarez-Bueno, Celia
多成分体育锻炼是老年人最推荐的体育干预类型。实验数据提示了肌脑轴的相关性以及肌肉收缩和脑源性神经营养因子释放之间的关系，然而，这种关系对认知的影响仍然不清楚，特别是在诊断为认知障碍的人中。这项研究评估了多成分体育锻炼对轻度认知障碍或痴呆症患者整体认知的影响。在三个电子数据库（PubMed、Scopus和科克伦数据库）中检索了截至2021年1月发表的随机对照试验。提取了多组分干预（耐力、力量、平衡或柔韧性）中包含的运动、有氧运动和整体认知变化的相关数据。效应量表示为标准化平均差异。通过RoB 2工具评估偏倚风险。共纳入8项研究。整体效应量表明多成分运动对整体认知的影响。然而，亚组分析显示，只有当有氧运动包括在干预措施中时才有效果。当轻度认知障碍和痴呆分别评估时没有效果被发现。这项研究表明，多组分体育锻炼可能会对轻度认知障碍或痴呆患者的整体认知产生影响，只有当有氧运动包括在干预措施中时。我们的研究结果支持将结构化的体育锻炼计划纳入认知障碍患者的管理中。在线版本包含补充材料，可通过10.1186/s12877-022-03302-1获得。
Multicomponent physical exercise is the most recommended type of physical intervention in older adults. Experimental data suggest the relevance of the muscle-brain axis and the relationship between muscle contraction and release of brain-derived neurotrophic factor, however, the impact of this relationship on cognition remains unclear, especially in people with diagnosis of cognitive impairment. This study assesses the effect of multicomponent physical exercise on global cognition in people with mild cognitive impairment or dementia. Randomized controlled trials published until January 2021 were searched across three electronic databases (PubMed, Scopus, and Cochrane Database). Data about exercises included in the multicomponent intervention (endurance, strength, balance, or flexibility), the inclusion of aerobic exercise, and the change in global cognition were extracted. The effect size was represented as a standardized mean difference. Risk of bias was assessed by the RoB2 tool. A total of 8 studies were included. The overall effect size suggested an effect of multicomponent exercise on global cognition. However, the subgroup analysis showed an effect only when aerobic exercise was included in the intervention. No effect when mild cognitive impairment and dementia were assessed separately was found. This study suggests that multicomponent physical exercise could have an effect on global cognition in people with mild cognitive impairment or dementia only when aerobic exercise is included in the intervention. Our results support the inclusion of structured physical exercise programs in the management of people with cognitive impairment. The online version contains supplementary material available at 10.1186/s12877-022-03302-1.
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影响因子：
4
作者：
Cancela, Jose M.;Ayan, Carlos;Seijo, Manuel
通讯作者：
Seijo, Manuel
体力活动可以改善阿尔茨海默病患者的认知：随机对照试验的系统回顾和荟萃分析
影响因子：
3.6
作者：
Du Z;Li Y;Li J;Zhou C;Li F;Yang X
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Yang X
影响因子：
2.5
作者：
Kwak, Y. -S.;Um, S. -Y.;Kim, D. -J.
通讯作者：
Kim, D. -J.
影响因子：
2.2
作者：
DerSimonian R;Laird N
通讯作者：
Laird N
影响因子：
6.3
作者：
de Souto Barreto, Philipe;Cesari, Matteo;Rolland, Yves
通讯作者：
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