Programmed subcellular release for studying the dynamics of cell detachment.

Programmed subcellular release for studying the dynamics of cell detachment.
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DOI:
10.1038/nmeth.1299
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发表时间:
2009-03
期刊:
影响因子:
48
通讯作者:
Searson, Peter C.
Searson, Peter C.
中科院分区:
生物学1区
文献类型:
--
作者:
Wildt, Bridget;Wirtz, Denis;Searson, Peter C.

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Cell detachment is central to a broad range of physiopathological changes, but there are no quantitative methods to study this process. Here we report programmed subcellular release, a method for spatially and temporally controlled cellular detachment, and present quantitative results of the detachment dynamics of 3T3 fibroblasts at the subcellular level.
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